| pubmed-article:20828803 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:20828803 | lifeskim:mentions | umls-concept:C0027651 | lld:lifeskim |
| pubmed-article:20828803 | lifeskim:mentions | umls-concept:C0043210 | lld:lifeskim |
| pubmed-article:20828803 | lifeskim:mentions | umls-concept:C0023610 | lld:lifeskim |
| pubmed-article:20828803 | lifeskim:mentions | umls-concept:C0243192 | lld:lifeskim |
| pubmed-article:20828803 | lifeskim:mentions | umls-concept:C0013089 | lld:lifeskim |
| pubmed-article:20828803 | lifeskim:mentions | umls-concept:C0178602 | lld:lifeskim |
| pubmed-article:20828803 | lifeskim:mentions | umls-concept:C0201734 | lld:lifeskim |
| pubmed-article:20828803 | lifeskim:mentions | umls-concept:C1704666 | lld:lifeskim |
| pubmed-article:20828803 | lifeskim:mentions | umls-concept:C1517892 | lld:lifeskim |
| pubmed-article:20828803 | lifeskim:mentions | umls-concept:C0208973 | lld:lifeskim |
| pubmed-article:20828803 | lifeskim:mentions | umls-concept:C0658617 | lld:lifeskim |
| pubmed-article:20828803 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:20828803 | pubmed:dateCreated | 2010-11-8 | lld:pubmed |
| pubmed-article:20828803 | pubmed:abstractText | Receptors for luteinizing hormone-releasing hormone (LHRH) can be utilized for targeted chemotherapy of cytotoxic LHRH analogs. The compound AEZS-108 (previously AN-152) consists of [D-Lys?]LHRH linked to doxorubicin. The objectives of this first study in humans with AESZ-108 were to determine the maximum tolerated dose and to characterize the dose-limiting toxicity, pharmacokinetics, preliminary efficacy, and hormonal effects. | lld:pubmed |
| pubmed-article:20828803 | pubmed:language | eng | lld:pubmed |
| pubmed-article:20828803 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20828803 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:20828803 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20828803 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20828803 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20828803 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20828803 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20828803 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20828803 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:20828803 | pubmed:month | Dec | lld:pubmed |
| pubmed-article:20828803 | pubmed:issn | 1095-6859 | lld:pubmed |
| pubmed-article:20828803 | pubmed:author | pubmed-author:GründkerCarst... | lld:pubmed |
| pubmed-article:20828803 | pubmed:author | pubmed-author:GünthertAndre... | lld:pubmed |
| pubmed-article:20828803 | pubmed:author | pubmed-author:EmonsGünterG | lld:pubmed |
| pubmed-article:20828803 | pubmed:author | pubmed-author:SchallyAndrew... | lld:pubmed |
| pubmed-article:20828803 | pubmed:author | pubmed-author:KaufmannManfr... | lld:pubmed |
| pubmed-article:20828803 | pubmed:author | pubmed-author:EngelJürgenJ | lld:pubmed |
| pubmed-article:20828803 | pubmed:author | pubmed-author:SindermannHer... | lld:pubmed |
| pubmed-article:20828803 | pubmed:author | pubmed-author:GorchevGrigor... | lld:pubmed |
| pubmed-article:20828803 | pubmed:author | pubmed-author:TsekovaValent... | lld:pubmed |
| pubmed-article:20828803 | pubmed:author | pubmed-author:HankerLars... | lld:pubmed |
| pubmed-article:20828803 | pubmed:author | pubmed-author:VelikovaMayaM | lld:pubmed |
| pubmed-article:20828803 | pubmed:copyrightInfo | Copyright © 2010 Elsevier Inc. All rights reserved. | lld:pubmed |
| pubmed-article:20828803 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:20828803 | pubmed:volume | 119 | lld:pubmed |
| pubmed-article:20828803 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:20828803 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:20828803 | pubmed:pagination | 457-61 | lld:pubmed |
| pubmed-article:20828803 | pubmed:meshHeading | pubmed-meshheading:20828803... | lld:pubmed |
| pubmed-article:20828803 | pubmed:meshHeading | pubmed-meshheading:20828803... | lld:pubmed |
| pubmed-article:20828803 | pubmed:meshHeading | pubmed-meshheading:20828803... | lld:pubmed |
| pubmed-article:20828803 | pubmed:meshHeading | pubmed-meshheading:20828803... | lld:pubmed |
| pubmed-article:20828803 | pubmed:meshHeading | pubmed-meshheading:20828803... | lld:pubmed |
| pubmed-article:20828803 | pubmed:meshHeading | pubmed-meshheading:20828803... | lld:pubmed |
| pubmed-article:20828803 | pubmed:meshHeading | pubmed-meshheading:20828803... | lld:pubmed |
| pubmed-article:20828803 | pubmed:meshHeading | pubmed-meshheading:20828803... | lld:pubmed |
| pubmed-article:20828803 | pubmed:meshHeading | pubmed-meshheading:20828803... | lld:pubmed |
| pubmed-article:20828803 | pubmed:meshHeading | pubmed-meshheading:20828803... | lld:pubmed |
| pubmed-article:20828803 | pubmed:meshHeading | pubmed-meshheading:20828803... | lld:pubmed |
| pubmed-article:20828803 | pubmed:meshHeading | pubmed-meshheading:20828803... | lld:pubmed |
| pubmed-article:20828803 | pubmed:meshHeading | pubmed-meshheading:20828803... | lld:pubmed |
| pubmed-article:20828803 | pubmed:meshHeading | pubmed-meshheading:20828803... | lld:pubmed |
| pubmed-article:20828803 | pubmed:year | 2010 | lld:pubmed |
| pubmed-article:20828803 | pubmed:articleTitle | Dose escalation and pharmacokinetic study of AEZS-108 (AN-152), an LHRH agonist linked to doxorubicin, in women with LHRH receptor-positive tumors. | lld:pubmed |
| pubmed-article:20828803 | pubmed:affiliation | University Clinic Göttingen, Göttingen, Germany. Emons@med.uni-goettingen.de | lld:pubmed |
| pubmed-article:20828803 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:20828803 | pubmed:publicationType | Clinical Trial | lld:pubmed |
| pubmed-article:20828803 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
