| pubmed-article:20723635 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:20723635 | lifeskim:mentions | umls-concept:C0008976 | lld:lifeskim |
| pubmed-article:20723635 | lifeskim:mentions | umls-concept:C0003842 | lld:lifeskim |
| pubmed-article:20723635 | lifeskim:mentions | umls-concept:C0085590 | lld:lifeskim |
| pubmed-article:20723635 | lifeskim:mentions | umls-concept:C0162578 | lld:lifeskim |
| pubmed-article:20723635 | lifeskim:mentions | umls-concept:C1522318 | lld:lifeskim |
| pubmed-article:20723635 | lifeskim:mentions | umls-concept:C1948041 | lld:lifeskim |
| pubmed-article:20723635 | lifeskim:mentions | umls-concept:C0376297 | lld:lifeskim |
| pubmed-article:20723635 | lifeskim:mentions | umls-concept:C0522523 | lld:lifeskim |
| pubmed-article:20723635 | lifeskim:mentions | umls-concept:C0699789 | lld:lifeskim |
| pubmed-article:20723635 | lifeskim:mentions | umls-concept:C0205225 | lld:lifeskim |
| pubmed-article:20723635 | pubmed:issue | 5 | lld:pubmed |
| pubmed-article:20723635 | pubmed:dateCreated | 2010-8-20 | lld:pubmed |
| pubmed-article:20723635 | pubmed:abstractText | In ST-segment elevation myocardial infarction (STEMI) impairment of microcirculatory function is a negative independent predictor of myocardial function recovery. In the Impact of Thrombectomy with EXPort Catheter in Infarct-Related Artery during Primary Percutaneous Coronary Intervention (PCI; EXPIRA) trial we found that manual thrombectomy resulted in a better myocardial reperfusion expressed by an improved procedural outcome and a decrease of infarct size compared to conventional PCI. The aim of the present study was to investigate whether the early efficacy of thrombus aspiration translates into very long-term clinical benefit. We randomized 175 patients with STEMI with occlusive thrombus at baseline undergoing primary PCI to thromboaspiration with a manual device (Export Medtronic, n = 88) or standard PCI (n = 87). No differences in baseline, clinical, and angiographic preprocedural findings were observed between the 2 groups except for incidence of hypertension and cholesterol levels. After 24 months major adverse cardiac events were 13.7% versus 4.5% (p = 0.038, log-rank test) and cardiac death was 6.8% versus 0% (p = 0.012, log-rank test). A strict correlation was observed between cardiac death incidence and tissue reperfusion parameters (postprocedural myocardial blush grade and ST-segment resolution). In conclusion, manual thrombus aspiration before stenting of the infarct-related artery in selected patients with STEMI improving myocardial reperfusion significantly decrease cardiac death and major adverse cardiac events at 2 years. | lld:pubmed |
| pubmed-article:20723635 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20723635 | pubmed:language | eng | lld:pubmed |
| pubmed-article:20723635 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20723635 | pubmed:citationSubset | AIM | lld:pubmed |
| pubmed-article:20723635 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:20723635 | pubmed:month | Sep | lld:pubmed |
| pubmed-article:20723635 | pubmed:issn | 1879-1913 | lld:pubmed |
| pubmed-article:20723635 | pubmed:author | pubmed-author:FedeleFrances... | lld:pubmed |
| pubmed-article:20723635 | pubmed:author | pubmed-author:ManconeMassim... | lld:pubmed |
| pubmed-article:20723635 | pubmed:author | pubmed-author:AgatiLucianoL | lld:pubmed |
| pubmed-article:20723635 | pubmed:author | pubmed-author:SardellaGenna... | lld:pubmed |
| pubmed-article:20723635 | pubmed:author | pubmed-author:BadagliaccaRo... | lld:pubmed |
| pubmed-article:20723635 | pubmed:author | pubmed-author:Di... | lld:pubmed |
| pubmed-article:20723635 | pubmed:author | pubmed-author:BenedettiGiul... | lld:pubmed |
| pubmed-article:20723635 | pubmed:author | pubmed-author:CanaliEmanuel... | lld:pubmed |
| pubmed-article:20723635 | pubmed:author | pubmed-author:LucisanoLuigi... | lld:pubmed |
| pubmed-article:20723635 | pubmed:author | pubmed-author:StioRoccoR | lld:pubmed |
| pubmed-article:20723635 | pubmed:copyrightInfo | 2010 Elsevier Inc. All rights reserved. | lld:pubmed |
| pubmed-article:20723635 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:20723635 | pubmed:day | 1 | lld:pubmed |
| pubmed-article:20723635 | pubmed:volume | 106 | lld:pubmed |
| pubmed-article:20723635 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:20723635 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:20723635 | pubmed:pagination | 624-9 | lld:pubmed |
| pubmed-article:20723635 | pubmed:dateRevised | 2011-5-2 | lld:pubmed |
| pubmed-article:20723635 | pubmed:meshHeading | pubmed-meshheading:20723635... | lld:pubmed |
| pubmed-article:20723635 | pubmed:meshHeading | pubmed-meshheading:20723635... | lld:pubmed |
| pubmed-article:20723635 | pubmed:meshHeading | pubmed-meshheading:20723635... | lld:pubmed |
| pubmed-article:20723635 | pubmed:meshHeading | pubmed-meshheading:20723635... | lld:pubmed |
| pubmed-article:20723635 | pubmed:meshHeading | pubmed-meshheading:20723635... | lld:pubmed |
| pubmed-article:20723635 | pubmed:meshHeading | pubmed-meshheading:20723635... | lld:pubmed |
| pubmed-article:20723635 | pubmed:meshHeading | pubmed-meshheading:20723635... | lld:pubmed |
| pubmed-article:20723635 | pubmed:meshHeading | pubmed-meshheading:20723635... | lld:pubmed |
| pubmed-article:20723635 | pubmed:meshHeading | pubmed-meshheading:20723635... | lld:pubmed |
| pubmed-article:20723635 | pubmed:meshHeading | pubmed-meshheading:20723635... | lld:pubmed |
| pubmed-article:20723635 | pubmed:meshHeading | pubmed-meshheading:20723635... | lld:pubmed |
| pubmed-article:20723635 | pubmed:meshHeading | pubmed-meshheading:20723635... | lld:pubmed |
| pubmed-article:20723635 | pubmed:meshHeading | pubmed-meshheading:20723635... | lld:pubmed |
| pubmed-article:20723635 | pubmed:meshHeading | pubmed-meshheading:20723635... | lld:pubmed |
| pubmed-article:20723635 | pubmed:year | 2010 | lld:pubmed |
| pubmed-article:20723635 | pubmed:articleTitle | Impact of thrombectomy with EXPort Catheter in Infarct-Related Artery during Primary Percutaneous Coronary Intervention (EXPIRA Trial) on cardiac death. | lld:pubmed |
| pubmed-article:20723635 | pubmed:affiliation | Department of Cardiovascular, Respiratory and Morphologic Sciences, "Sapienza" University, Policlinico "Umberto I", Rome, Italy. rino.sardella@Uniroma1.it | lld:pubmed |
| pubmed-article:20723635 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:20723635 | pubmed:publicationType | Randomized Controlled Trial | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:20723635 | lld:pubmed |
