pubmed-article:20637112 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:20637112 | lifeskim:mentions | umls-concept:C0027651 | lld:lifeskim |
pubmed-article:20637112 | lifeskim:mentions | umls-concept:C0035820 | lld:lifeskim |
pubmed-article:20637112 | lifeskim:mentions | umls-concept:C0012472 | lld:lifeskim |
pubmed-article:20637112 | lifeskim:mentions | umls-concept:C0033559 | lld:lifeskim |
pubmed-article:20637112 | lifeskim:mentions | umls-concept:C1411976 | lld:lifeskim |
pubmed-article:20637112 | lifeskim:mentions | umls-concept:C0127400 | lld:lifeskim |
pubmed-article:20637112 | pubmed:dateCreated | 2010-8-2 | lld:pubmed |
pubmed-article:20637112 | pubmed:abstractText | We have previously found that TLR4-deficient (TLR4-/-) mice demonstrate decreased expression of mucosal PGE 2 and are protected against colitis-associated neoplasia. However, it is still unclear whether PGE 2 is the central factor downstream of TLR4 signaling that promotes intestinal tumorigenesis. To further elucidate critical downstream pathways involving TLR4-mediated intestinal tumorigenesis, we examined the effects of exogenously administered PGE 2 in TLR4-/- mice to see if PGE 2 bypasses the protection from colitis-associated tumorigenesis. | lld:pubmed |
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pubmed-article:20637112 | pubmed:language | eng | lld:pubmed |
pubmed-article:20637112 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:20637112 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:20637112 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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pubmed-article:20637112 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:20637112 | pubmed:issn | 1471-230X | lld:pubmed |
pubmed-article:20637112 | pubmed:author | pubmed-author:XuRuliangR | lld:pubmed |
pubmed-article:20637112 | pubmed:author | pubmed-author:AbreuMaria... | lld:pubmed |
pubmed-article:20637112 | pubmed:author | pubmed-author:ChenAnliA | lld:pubmed |
pubmed-article:20637112 | pubmed:author | pubmed-author:HsuDavidD | lld:pubmed |
pubmed-article:20637112 | pubmed:author | pubmed-author:HayesLory ALA | lld:pubmed |
pubmed-article:20637112 | pubmed:author | pubmed-author:FukataMasayuk... | lld:pubmed |
pubmed-article:20637112 | pubmed:author | pubmed-author:HernandezYasm... | lld:pubmed |
pubmed-article:20637112 | pubmed:author | pubmed-author:BreglioKeithK | lld:pubmed |