| pubmed-article:20621380 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:20621380 | lifeskim:mentions | umls-concept:C0013303 | lld:lifeskim |
| pubmed-article:20621380 | lifeskim:mentions | umls-concept:C0030274 | lld:lifeskim |
| pubmed-article:20621380 | lifeskim:mentions | umls-concept:C0013126 | lld:lifeskim |
| pubmed-article:20621380 | lifeskim:mentions | umls-concept:C0017262 | lld:lifeskim |
| pubmed-article:20621380 | lifeskim:mentions | umls-concept:C2610414 | lld:lifeskim |
| pubmed-article:20621380 | lifeskim:mentions | umls-concept:C1515568 | lld:lifeskim |
| pubmed-article:20621380 | lifeskim:mentions | umls-concept:C2911684 | lld:lifeskim |
| pubmed-article:20621380 | lifeskim:mentions | umls-concept:C0185117 | lld:lifeskim |
| pubmed-article:20621380 | pubmed:issue | 4 | lld:pubmed |
| pubmed-article:20621380 | pubmed:dateCreated | 2010-8-30 | lld:pubmed |
| pubmed-article:20621380 | pubmed:abstractText | Reactive cholangiocytes acquire a neuroendocrine-like phenotype, with synthesis and local release of neuropeptides and hormones. The mechanism that drives such phenotypical changes is still undefined. Pancreatic Duodenal Homeobox-1 (PDX-1) is a transcription factor required for pancreatic development, that sustains pancreatic beta-cell response to injury and insulin synthesis. PDX-1 induces neuroendocrine-like transition of pancreatic ductal cells. Cholangiocyte response to injury is modulated by Glucagon-Like Peptide-1 Receptor (GLP-1R), which, in the pancreas, activates PDX-1. We wanted to verify whether PDX-1 plays any role in cholangiocyte neuroendocrine-like transdifferentiation in response to injury. | lld:pubmed |
| pubmed-article:20621380 | pubmed:language | eng | lld:pubmed |
| pubmed-article:20621380 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20621380 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:20621380 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20621380 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20621380 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20621380 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:20621380 | pubmed:month | Oct | lld:pubmed |
| pubmed-article:20621380 | pubmed:issn | 0168-8278 | lld:pubmed |
| pubmed-article:20621380 | pubmed:author | pubmed-author:MarzioniMarco... | lld:pubmed |
| pubmed-article:20621380 | pubmed:author | pubmed-author:TrozziLuciano... | lld:pubmed |
| pubmed-article:20621380 | pubmed:author | pubmed-author:SaccomannoSte... | lld:pubmed |
| pubmed-article:20621380 | pubmed:author | pubmed-author:BenedettiAnto... | lld:pubmed |
| pubmed-article:20621380 | pubmed:author | pubmed-author:CandelaresiCi... | lld:pubmed |
| pubmed-article:20621380 | pubmed:author | pubmed-author:De... | lld:pubmed |
| pubmed-article:20621380 | pubmed:author | pubmed-author:ShanmukhappaK... | lld:pubmed |
| pubmed-article:20621380 | pubmed:author | pubmed-author:AgostinelliLa... | lld:pubmed |
| pubmed-article:20621380 | pubmed:author | pubmed-author:RychlickiChia... | lld:pubmed |
| pubmed-article:20621380 | pubmed:author | pubmed-author:Pierantonelli... | lld:pubmed |
| pubmed-article:20621380 | pubmed:copyrightInfo | Copyright © 2010 European Association for the Study of the Liver. Published by Elsevier B.V. All rights reserved. | lld:pubmed |
| pubmed-article:20621380 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:20621380 | pubmed:volume | 53 | lld:pubmed |
| pubmed-article:20621380 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:20621380 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:20621380 | pubmed:pagination | 663-70 | lld:pubmed |
| pubmed-article:20621380 | pubmed:dateRevised | 2011-6-1 | lld:pubmed |
| pubmed-article:20621380 | pubmed:meshHeading | pubmed-meshheading:20621380... | lld:pubmed |
| pubmed-article:20621380 | pubmed:meshHeading | pubmed-meshheading:20621380... | lld:pubmed |
| pubmed-article:20621380 | pubmed:meshHeading | pubmed-meshheading:20621380... | lld:pubmed |
| pubmed-article:20621380 | pubmed:meshHeading | pubmed-meshheading:20621380... | lld:pubmed |
| pubmed-article:20621380 | pubmed:meshHeading | pubmed-meshheading:20621380... | lld:pubmed |
| pubmed-article:20621380 | pubmed:meshHeading | pubmed-meshheading:20621380... | lld:pubmed |
| pubmed-article:20621380 | pubmed:meshHeading | pubmed-meshheading:20621380... | lld:pubmed |
| pubmed-article:20621380 | pubmed:meshHeading | pubmed-meshheading:20621380... | lld:pubmed |
| pubmed-article:20621380 | pubmed:meshHeading | pubmed-meshheading:20621380... | lld:pubmed |
| pubmed-article:20621380 | pubmed:year | 2010 | lld:pubmed |
| pubmed-article:20621380 | pubmed:articleTitle | Pancreatic Duodenal Homeobox-1 de novo expression drives cholangiocyte neuroendocrine-like transdifferentiation. | lld:pubmed |
| pubmed-article:20621380 | pubmed:affiliation | Department of Gastroenterology, Università Politecnica delle Marche, Ancona, Italy. m.marzioni@univpm.it | lld:pubmed |
| pubmed-article:20621380 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:20621380 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
