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pubmed-article:20596538pubmed:abstractTextAn increasing number of patients have medical conditions with altered host immunity or that require immunosuppressive medications. While immunosuppression is associated with increased risk of infection, the precise effect of immunosuppression on innate immunity is not well understood. We studied monocyte Toll-like receptor (TLR) expression and cytokine production in 137 patients with autoimmune diseases who were maintained on immunosuppressive medications and 419 non-immunosuppressed individuals.lld:pubmed
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pubmed-article:20596538pubmed:articleTitleIncreased TLR4 expression and downstream cytokine production in immunosuppressed adults compared to non-immunosuppressed adults.lld:pubmed
pubmed-article:20596538pubmed:affiliationDepartment of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut, United States of America. dana.dunne@yale.edulld:pubmed
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