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pubmed-article:20459441rdf:typepubmed:Citationlld:pubmed
pubmed-article:20459441lifeskim:mentionsumls-concept:C0442115lld:lifeskim
pubmed-article:20459441lifeskim:mentionsumls-concept:C0039593lld:lifeskim
pubmed-article:20459441lifeskim:mentionsumls-concept:C0680240lld:lifeskim
pubmed-article:20459441pubmed:issue7lld:pubmed
pubmed-article:20459441pubmed:dateCreated2010-10-5lld:pubmed
pubmed-article:20459441pubmed:abstractTextTwenty-four-hour ambulatory multichannel intraluminal impedance (MII)-pH detects both acid and nonacid reflux (NAR). A computer-based program (Autoscan™, Sandhill Scientific, Highlands Ranch, CO, USA) automates the detection of reflux episodes, increasing the ease of study interpretation. Inter-observer agreement between multiple reviewers and with Autoscan™ for the evaluation of significant NAR with MII-pH has not been studied in the adult population. Twenty MII-pH studies on patients taking a proton pump inhibitor twice daily were randomly selected. Autoscan™ analyzed all studies using the same pre-programmed parameters. Four reviewers interpreted the MII-pH studies, adding or deleting reflux episodes detected by Autoscan™. Positive studies for NAR and total reflux episodes were based on published criteria. Cohen's kappa statistic (?) evaluated inter-observer agreement between reviewers and Autoscan™ analysis. The average ? for pathologic NAR between reviewers was 0.57 (0.47-0.70), and between reviewers and Autoscan™ was 0.56 (0.4-0.8). When using the total reflux episode number as a marker for pathologic reflux (acid and NAR), the ? score was 0.72 (0.61-0.89) between reviewers, and 0.74 (0.53-0.9) when evaluating total reflux episodes. Two reviewers agreed more often with each other and with Autoscan™ on the number of NAR episodes, while the other two reviewers agreed with each other, but did not agree with either Autoscan™ or the first two reviewers. Inter-observer agreement between reviewers and Autoscan™ for detecting pathologic NAR is moderate, with reviewers either excluding more of the Autoscan™-defined events or excluding fewer events and therefore agreeing with Autoscan™.lld:pubmed
pubmed-article:20459441pubmed:languageenglld:pubmed
pubmed-article:20459441pubmed:journalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:20459441pubmed:citationSubsetIMlld:pubmed
pubmed-article:20459441pubmed:statusMEDLINElld:pubmed
pubmed-article:20459441pubmed:monthSeplld:pubmed
pubmed-article:20459441pubmed:issn1442-2050lld:pubmed
pubmed-article:20459441pubmed:authorpubmed-author:FrancisD LDLlld:pubmed
pubmed-article:20459441pubmed:authorpubmed-author:MurrayJ AJAlld:pubmed
pubmed-article:20459441pubmed:authorpubmed-author:RaviKKlld:pubmed
pubmed-article:20459441pubmed:authorpubmed-author:DeVaultK RKRlld:pubmed
pubmed-article:20459441pubmed:authorpubmed-author:BourasE PEPlld:pubmed
pubmed-article:20459441pubmed:copyrightInfo© 2010 Copyright the Authors. Journal compilation © 2010, Wiley Periodicals, Inc. and the International Society for Diseases of the Esophagus.lld:pubmed
pubmed-article:20459441pubmed:issnTypeElectroniclld:pubmed
pubmed-article:20459441pubmed:volume23lld:pubmed
pubmed-article:20459441pubmed:ownerNLMlld:pubmed
pubmed-article:20459441pubmed:authorsCompleteYlld:pubmed
pubmed-article:20459441pubmed:pagination540-4lld:pubmed
pubmed-article:20459441pubmed:meshHeadingpubmed-meshheading:20459441...lld:pubmed
pubmed-article:20459441pubmed:meshHeadingpubmed-meshheading:20459441...lld:pubmed
pubmed-article:20459441pubmed:meshHeadingpubmed-meshheading:20459441...lld:pubmed
pubmed-article:20459441pubmed:meshHeadingpubmed-meshheading:20459441...lld:pubmed
pubmed-article:20459441pubmed:year2010lld:pubmed
pubmed-article:20459441pubmed:articleTitleInter-observer agreement for multichannel intraluminal impedance-pH testing.lld:pubmed
pubmed-article:20459441pubmed:affiliationDivision of Gastroenterology and Hepatology, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN 55905, USA.lld:pubmed
pubmed-article:20459441pubmed:publicationTypeJournal Articlelld:pubmed