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pubmed-article:20442586pubmed:abstractTextTraditionally, ovarian serous carcinomas (OSCs) have been graded using a 3-tiered system, as well differentiated, moderately differentiated, and poorly differentiated. Recently, a 2-tiered system has been proposed depending on the nuclear atypia and mitotic count. The dualistic pathway of ovarian serous carcinogenesis with accumulating molecular genetic evidence forms the basis for this grading system.lld:pubmed
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pubmed-article:20442586pubmed:articleTitleAn immunohistochemical comparison of P53 and Bcl-2 as apoptotic and MIB1 as proliferative markers in low-grade and high-grade ovarian serous carcinomas.lld:pubmed
pubmed-article:20442586pubmed:affiliationDepartment of Pathology, St John's Medical College, Bangalore, Karnataka, India.lld:pubmed
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