| pubmed-article:20371689 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:20371689 | lifeskim:mentions | umls-concept:C0030705 | lld:lifeskim |
| pubmed-article:20371689 | lifeskim:mentions | umls-concept:C0086418 | lld:lifeskim |
| pubmed-article:20371689 | lifeskim:mentions | umls-concept:C0332174 | lld:lifeskim |
| pubmed-article:20371689 | lifeskim:mentions | umls-concept:C0003250 | lld:lifeskim |
| pubmed-article:20371689 | lifeskim:mentions | umls-concept:C0280100 | lld:lifeskim |
| pubmed-article:20371689 | lifeskim:mentions | umls-concept:C0140080 | lld:lifeskim |
| pubmed-article:20371689 | lifeskim:mentions | umls-concept:C2346815 | lld:lifeskim |
| pubmed-article:20371689 | lifeskim:mentions | umls-concept:C0231491 | lld:lifeskim |
| pubmed-article:20371689 | lifeskim:mentions | umls-concept:C0920321 | lld:lifeskim |
| pubmed-article:20371689 | lifeskim:mentions | umls-concept:C0205179 | lld:lifeskim |
| pubmed-article:20371689 | pubmed:issue | 8 | lld:pubmed |
| pubmed-article:20371689 | pubmed:dateCreated | 2010-4-16 | lld:pubmed |
| pubmed-article:20371689 | pubmed:abstractText | A phase I study was conducted to evaluate the pharmacokinetics, pharmacodynamics, safety, and tolerability of R1507-a fully human IgG1 type monoclonal antibody directed against the human insulin-like growth factor-I receptor. Experimental design: Patients with advanced solid tumors were assigned to receive i.v. R1507 weekly (qW), starting with 1 mg/kg. Subsequent cohorts were dosed at 3 and then 9 mg/kg. An additional 12 patients received 9 mg/kg R1507 qW. Patients remained on the study until the development of a dose-limiting toxicity or progressive disease. | lld:pubmed |
| pubmed-article:20371689 | pubmed:language | eng | lld:pubmed |
| pubmed-article:20371689 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20371689 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:20371689 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20371689 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20371689 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:20371689 | pubmed:month | Apr | lld:pubmed |
| pubmed-article:20371689 | pubmed:issn | 1078-0432 | lld:pubmed |
| pubmed-article:20371689 | pubmed:author | pubmed-author:PatnaikAmitaA | lld:pubmed |
| pubmed-article:20371689 | pubmed:author | pubmed-author:EckhardtS... | lld:pubmed |
| pubmed-article:20371689 | pubmed:author | pubmed-author:AisnerJosephJ | lld:pubmed |
| pubmed-article:20371689 | pubmed:author | pubmed-author:KurzrockRazel... | lld:pubmed |
| pubmed-article:20371689 | pubmed:author | pubmed-author:WarrenTerriT | lld:pubmed |
| pubmed-article:20371689 | pubmed:author | pubmed-author:GoreLiaL | lld:pubmed |
| pubmed-article:20371689 | pubmed:author | pubmed-author:GreigGerardG | lld:pubmed |
| pubmed-article:20371689 | pubmed:author | pubmed-author:EidJoseph EJE | lld:pubmed |
| pubmed-article:20371689 | pubmed:author | pubmed-author:BenjaminRober... | lld:pubmed |
| pubmed-article:20371689 | pubmed:author | pubmed-author:HabbenKaiK | lld:pubmed |
| pubmed-article:20371689 | pubmed:author | pubmed-author:LeongStephenS | lld:pubmed |
| pubmed-article:20371689 | pubmed:author | pubmed-author:McCarthyCinar... | lld:pubmed |
| pubmed-article:20371689 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:20371689 | pubmed:day | 15 | lld:pubmed |
| pubmed-article:20371689 | pubmed:volume | 16 | lld:pubmed |
| pubmed-article:20371689 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:20371689 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:20371689 | pubmed:pagination | 2458-65 | lld:pubmed |
| pubmed-article:20371689 | pubmed:dateRevised | 2011-8-2 | lld:pubmed |
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| pubmed-article:20371689 | pubmed:meshHeading | pubmed-meshheading:20371689... | lld:pubmed |
| pubmed-article:20371689 | pubmed:year | 2010 | lld:pubmed |
| pubmed-article:20371689 | pubmed:articleTitle | A phase I study of weekly R1507, a human monoclonal antibody insulin-like growth factor-I receptor antagonist, in patients with advanced solid tumors. | lld:pubmed |
| pubmed-article:20371689 | pubmed:affiliation | Department of Investigational Cancer Therapeutics, M.D. Anderson Cancer Center, Houston, TX 77030, USA. rkurzroc@mdanderson.org | lld:pubmed |
| pubmed-article:20371689 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:20371689 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| pubmed-article:20371689 | pubmed:publicationType | Clinical Trial, Phase I | lld:pubmed |
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