pubmed-article:20347304 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:20347304 | lifeskim:mentions | umls-concept:C0001443 | lld:lifeskim |
pubmed-article:20347304 | lifeskim:mentions | umls-concept:C0002508 | lld:lifeskim |
pubmed-article:20347304 | lifeskim:mentions | umls-concept:C0243076 | lld:lifeskim |
pubmed-article:20347304 | pubmed:issue | 9 | lld:pubmed |
pubmed-article:20347304 | pubmed:dateCreated | 2010-4-20 | lld:pubmed |
pubmed-article:20347304 | pubmed:abstractText | A novel series of arylindenopyrimidines were identified as A(2A) and A(1) receptor antagonists. The series was optimized for in vitro activity by substituting the 8- and 9-positions with methylene amine substituents. The compounds show excellent activity in mouse models of Parkinson's disease when dosed orally. | lld:pubmed |
pubmed-article:20347304 | pubmed:language | eng | lld:pubmed |
pubmed-article:20347304 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:20347304 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:20347304 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:20347304 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:20347304 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:20347304 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:20347304 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:20347304 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:20347304 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:20347304 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:20347304 | pubmed:month | May | lld:pubmed |
pubmed-article:20347304 | pubmed:issn | 1464-3405 | lld:pubmed |
pubmed-article:20347304 | pubmed:author | pubmed-author:HeintzelmanGe... | lld:pubmed |
pubmed-article:20347304 | pubmed:author | pubmed-author:ShookBrian... | lld:pubmed |
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pubmed-article:20347304 | pubmed:author | pubmed-author:RupertKenneth... | lld:pubmed |
pubmed-article:20347304 | pubmed:author | pubmed-author:LiXunX | lld:pubmed |
pubmed-article:20347304 | pubmed:author | pubmed-author:HallDanielD | lld:pubmed |
pubmed-article:20347304 | pubmed:author | pubmed-author:WellsKennethK | lld:pubmed |
pubmed-article:20347304 | pubmed:author | pubmed-author:RhodesKenneth... | lld:pubmed |
pubmed-article:20347304 | pubmed:author | pubmed-author:DemarestKeith... | lld:pubmed |
pubmed-article:20347304 | pubmed:author | pubmed-author:TangYutingY | lld:pubmed |
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pubmed-article:20347304 | pubmed:author | pubmed-author:RussellRonald... | lld:pubmed |
pubmed-article:20347304 | pubmed:author | pubmed-author:LampronLisaL | lld:pubmed |
pubmed-article:20347304 | pubmed:author | pubmed-author:BranumShawnS | lld:pubmed |
pubmed-article:20347304 | pubmed:author | pubmed-author:DamonSandraS | lld:pubmed |
pubmed-article:20347304 | pubmed:author | pubmed-author:YouellsScottS | lld:pubmed |
pubmed-article:20347304 | pubmed:author | pubmed-author:MagliaroBrian... | lld:pubmed |
pubmed-article:20347304 | pubmed:author | pubmed-author:OsbourneMelM | lld:pubmed |
pubmed-article:20347304 | pubmed:copyrightInfo | 2010 Elsevier Ltd. All rights reserved. | lld:pubmed |
pubmed-article:20347304 | pubmed:issnType | Electronic | lld:pubmed |
pubmed-article:20347304 | pubmed:day | 1 | lld:pubmed |
pubmed-article:20347304 | pubmed:volume | 20 | lld:pubmed |
pubmed-article:20347304 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:20347304 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:20347304 | pubmed:pagination | 2864-7 | lld:pubmed |
pubmed-article:20347304 | pubmed:dateRevised | 2010-11-18 | lld:pubmed |
pubmed-article:20347304 | pubmed:meshHeading | pubmed-meshheading:20347304... | lld:pubmed |
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pubmed-article:20347304 | pubmed:meshHeading | pubmed-meshheading:20347304... | lld:pubmed |
pubmed-article:20347304 | pubmed:year | 2010 | lld:pubmed |
pubmed-article:20347304 | pubmed:articleTitle | Methylene amine substituted arylindenopyrimidines as potent adenosine A(2A)/A(1) antagonists. | lld:pubmed |
pubmed-article:20347304 | pubmed:affiliation | Johnson & Johnson Pharmaceutical Research and Development, L.L.C., Welsh and McKean Roads, PO Box 776, Spring House, PA 19477, United States. bshook@its.jnj.com | lld:pubmed |
pubmed-article:20347304 | pubmed:publicationType | Journal Article | lld:pubmed |
http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | pubmed-article:20347304 | lld:chembl |