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pubmed-article:20332317pubmed:abstractTextNuclear receptor coactivator expression and activity may partly explain the complex agonist/antagonist effects of tamoxifen at clinical level. In a preoperative trial, dose reduction from 20 to 1 mg tamoxifen was associated with retained antiproliferative effect on breast cancer. Here, we assessed the gene expression of the steroid receptor coactivators SRC-1, SRC-2/transcription intermediary factor 2, and SRC-3/amplified in breast cancer 1 (AIB1) and the growth factor receptor HER-2/neu under three tamoxifen dose regimens.lld:pubmed
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pubmed-article:20332317pubmed:copyrightInfoCopyright 2010 AACR.lld:pubmed
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pubmed-article:20332317pubmed:dateRevised2010-10-20lld:pubmed
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pubmed-article:20332317pubmed:year2010lld:pubmed
pubmed-article:20332317pubmed:articleTitleEffect of low-dose tamoxifen on steroid receptor coactivator 3/amplified in breast cancer 1 in normal and malignant human breast tissue.lld:pubmed
pubmed-article:20332317pubmed:affiliationInstitute of Medicine, University of Bergen, Hormone Laboratory, Haukeland University Hospital, Bergen, Norway.lld:pubmed
pubmed-article:20332317pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:20332317pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed
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