pubmed-article:2015653 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:2015653 | lifeskim:mentions | umls-concept:C0040135 | lld:lifeskim |
pubmed-article:2015653 | lifeskim:mentions | umls-concept:C0007585 | lld:lifeskim |
pubmed-article:2015653 | lifeskim:mentions | umls-concept:C1159339 | lld:lifeskim |
pubmed-article:2015653 | lifeskim:mentions | umls-concept:C0543482 | lld:lifeskim |
pubmed-article:2015653 | lifeskim:mentions | umls-concept:C0441472 | lld:lifeskim |
pubmed-article:2015653 | lifeskim:mentions | umls-concept:C0392747 | lld:lifeskim |
pubmed-article:2015653 | lifeskim:mentions | umls-concept:C0205263 | lld:lifeskim |
pubmed-article:2015653 | pubmed:issue | 1 | lld:pubmed |
pubmed-article:2015653 | pubmed:dateCreated | 1991-5-22 | lld:pubmed |
pubmed-article:2015653 | pubmed:abstractText | The effects of triiodothyronine (T3) on cell morphology and protein secretion were examined in astrocytes cultured in a chemically defined medium devoid of other hormones and growth factors. The flat polygonal astrocytic cells treated with T3 (1-50 nM) and maintained in non-renewed medium cultures were progressively transformed into process-bearing cells. These changes were initially observed 3 days after the end of T3 treatment and accounted for more than 50% of the cells 7-8 days thereafter. The proteins secreted by the T3-stimulated cells were analyzed on SDS-PAGE after cell labeling for 4.5 h with [35S]methionine. The effect of T3 on protein secretion was dose-dependent. Half-maximal stimulation was reached with 0.2-0.5 nM hormone and the proteins of 46, 59, 67, 78, 85 and 140 kDa were over-secreted (greater than 300% of control). These results were only obtained when the cell medium was not renewed after T3 treatment. | lld:pubmed |
pubmed-article:2015653 | pubmed:language | eng | lld:pubmed |
pubmed-article:2015653 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2015653 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:2015653 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2015653 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2015653 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:2015653 | pubmed:month | Jan | lld:pubmed |
pubmed-article:2015653 | pubmed:issn | 0165-3806 | lld:pubmed |
pubmed-article:2015653 | pubmed:author | pubmed-author:PierreMM | lld:pubmed |
pubmed-article:2015653 | pubmed:author | pubmed-author:GavaretJ MJM | lld:pubmed |
pubmed-article:2015653 | pubmed:author | pubmed-author:PomeranceMM | lld:pubmed |
pubmed-article:2015653 | pubmed:author | pubmed-author:Toru-Delbauff... | lld:pubmed |
pubmed-article:2015653 | pubmed:author | pubmed-author:Baghdassarian... | lld:pubmed |
pubmed-article:2015653 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:2015653 | pubmed:day | 15 | lld:pubmed |
pubmed-article:2015653 | pubmed:volume | 58 | lld:pubmed |
pubmed-article:2015653 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:2015653 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:2015653 | pubmed:pagination | 43-9 | lld:pubmed |
pubmed-article:2015653 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
pubmed-article:2015653 | pubmed:meshHeading | pubmed-meshheading:2015653-... | lld:pubmed |
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pubmed-article:2015653 | pubmed:meshHeading | pubmed-meshheading:2015653-... | lld:pubmed |
pubmed-article:2015653 | pubmed:year | 1991 | lld:pubmed |
pubmed-article:2015653 | pubmed:articleTitle | Thyroid hormone action: induction of morphological changes and protein secretion in astroglial cell cultures. | lld:pubmed |
pubmed-article:2015653 | pubmed:affiliation | U. 96 INSERM, Unité de Recherche sur la Glande Thyroïde et Régulation Hormonale, Le Kremlin-Bicêtre, France. | lld:pubmed |
pubmed-article:2015653 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:2015653 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2015653 | lld:pubmed |