| pubmed-article:201458 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:201458 | lifeskim:mentions | umls-concept:C0282151 | lld:lifeskim |
| pubmed-article:201458 | lifeskim:mentions | umls-concept:C0441655 | lld:lifeskim |
| pubmed-article:201458 | lifeskim:mentions | umls-concept:C1280500 | lld:lifeskim |
| pubmed-article:201458 | lifeskim:mentions | umls-concept:C1948023 | lld:lifeskim |
| pubmed-article:201458 | lifeskim:mentions | umls-concept:C0205195 | lld:lifeskim |
| pubmed-article:201458 | pubmed:issue | 4 | lld:pubmed |
| pubmed-article:201458 | pubmed:dateCreated | 1978-2-18 | lld:pubmed |
| pubmed-article:201458 | pubmed:abstractText | In this study we tested a hypothesis that dopamine and GABA receptor-stimulating agents given together might mutually potentiate their anticonvulsant activities. To test this hypothesis, experiments were performed on free-moving rabbits with epileptiform activity evoked by cortical application of ouabain. After combined treatment with apomorphine and GHBA 3 out of 6 animals displayed no EEG epileptiform activity, and in the remaining 3 rabbits this activity was greatly reduced. A combined pretreatment with apomorphine and GHBA abolished epileptiform EEG activity during the first hour and shortened it during the second hour, but not significantly. Apomorphine given together with amino-oxyacetic acid before ouabain completely abolished the epileptiform activity in 4 out of 6 animals. In the remaining 2 rabbits the latency of ouabain affect was prolonged, the epileptiform activity during the first hour was abolished, and it was markedly decreased during the next 2 hr (significantly from controls or groups receiving apomorphine or amino-oxyacetic acid). Phenytoin was less potent than apomorphine with GHBA or apomorphine given together with AOAA. The animals' behavior was observed. | lld:pubmed |
| pubmed-article:201458 | pubmed:language | eng | lld:pubmed |
| pubmed-article:201458 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:201458 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:201458 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:201458 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:201458 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:201458 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:201458 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:201458 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:201458 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:201458 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:201458 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:201458 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:201458 | pubmed:month | Dec | lld:pubmed |
| pubmed-article:201458 | pubmed:issn | 0013-9580 | lld:pubmed |
| pubmed-article:201458 | pubmed:author | pubmed-author:StachRR | lld:pubmed |
| pubmed-article:201458 | pubmed:author | pubmed-author:KaczDD | lld:pubmed |
| pubmed-article:201458 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:201458 | pubmed:volume | 18 | lld:pubmed |
| pubmed-article:201458 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:201458 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:201458 | pubmed:pagination | 417-23 | lld:pubmed |
| pubmed-article:201458 | pubmed:dateRevised | 2004-11-17 | lld:pubmed |
| pubmed-article:201458 | pubmed:meshHeading | pubmed-meshheading:201458-A... | lld:pubmed |
| pubmed-article:201458 | pubmed:meshHeading | pubmed-meshheading:201458-S... | lld:pubmed |
| pubmed-article:201458 | pubmed:meshHeading | pubmed-meshheading:201458-H... | lld:pubmed |
| pubmed-article:201458 | pubmed:meshHeading | pubmed-meshheading:201458-R... | lld:pubmed |
| pubmed-article:201458 | pubmed:meshHeading | pubmed-meshheading:201458-P... | lld:pubmed |
| pubmed-article:201458 | pubmed:meshHeading | pubmed-meshheading:201458-D... | lld:pubmed |
| pubmed-article:201458 | pubmed:meshHeading | pubmed-meshheading:201458-M... | lld:pubmed |
| pubmed-article:201458 | pubmed:meshHeading | pubmed-meshheading:201458-E... | lld:pubmed |
| pubmed-article:201458 | pubmed:meshHeading | pubmed-meshheading:201458-A... | lld:pubmed |
| pubmed-article:201458 | pubmed:meshHeading | pubmed-meshheading:201458-O... | lld:pubmed |
| pubmed-article:201458 | pubmed:meshHeading | pubmed-meshheading:201458-C... | lld:pubmed |
| pubmed-article:201458 | pubmed:meshHeading | pubmed-meshheading:201458-g... | lld:pubmed |
| pubmed-article:201458 | pubmed:meshHeading | pubmed-meshheading:201458-D... | lld:pubmed |
| pubmed-article:201458 | pubmed:meshHeading | pubmed-meshheading:201458-R... | lld:pubmed |
| pubmed-article:201458 | pubmed:meshHeading | pubmed-meshheading:201458-A... | lld:pubmed |
| pubmed-article:201458 | pubmed:meshHeading | pubmed-meshheading:201458-R... | lld:pubmed |
| pubmed-article:201458 | pubmed:year | 1977 | lld:pubmed |
| pubmed-article:201458 | pubmed:articleTitle | Effect of combined dopaminergic and GABA-ergic stimulation on ouabain-induced epileptiform activity. | lld:pubmed |
| pubmed-article:201458 | pubmed:publicationType | Journal Article | lld:pubmed |
