pubmed-article:20105326 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:20105326 | lifeskim:mentions | umls-concept:C0034802 | lld:lifeskim |
pubmed-article:20105326 | lifeskim:mentions | umls-concept:C0037083 | lld:lifeskim |
pubmed-article:20105326 | lifeskim:mentions | umls-concept:C0023688 | lld:lifeskim |
pubmed-article:20105326 | lifeskim:mentions | umls-concept:C1710082 | lld:lifeskim |
pubmed-article:20105326 | pubmed:dateCreated | 2010-3-9 | lld:pubmed |
pubmed-article:20105326 | pubmed:abstractText | The epidermal growth factor receptor (Egfr) with its numerous ligands has fundamental roles in development, cell differentiation and physiology. Dysfunction of the receptor-ligand system contributes to many human malignancies. Consistent with such various tasks, the Egfr gene family has expanded during vertebrate evolution as a consequence of several rounds of whole genome duplication. Of particular interest is the effect of the fish-specific whole genome duplication (FSGD) on the ligand-receptor system, as it has supplied this largest group of vertebrates with additional opportunities for sub- and/or neofunctionalization in this signaling system. | lld:pubmed |
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pubmed-article:20105326 | pubmed:language | eng | lld:pubmed |
pubmed-article:20105326 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:20105326 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:20105326 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:20105326 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:20105326 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:20105326 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:20105326 | pubmed:issn | 1471-2148 | lld:pubmed |
pubmed-article:20105326 | pubmed:author | pubmed-author:SchartlManfre... | lld:pubmed |
pubmed-article:20105326 | pubmed:author | pubmed-author:WalterRonald... | lld:pubmed |
pubmed-article:20105326 | pubmed:author | pubmed-author:MeierjohannSv... | lld:pubmed |
pubmed-article:20105326 | pubmed:author | pubmed-author:BraaschIngoI | lld:pubmed |
pubmed-article:20105326 | pubmed:author | pubmed-author:LaisneyJuliet... | lld:pubmed |
pubmed-article:20105326 | pubmed:issnType | Electronic | lld:pubmed |
pubmed-article:20105326 | pubmed:volume | 10 | lld:pubmed |
pubmed-article:20105326 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:20105326 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:20105326 | pubmed:pagination | 27 | lld:pubmed |
pubmed-article:20105326 | pubmed:dateRevised | 2011-9-26 | lld:pubmed |
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pubmed-article:20105326 | pubmed:year | 2010 | lld:pubmed |
pubmed-article:20105326 | pubmed:articleTitle | Lineage-specific co-evolution of the Egf receptor/ligand signaling system. | lld:pubmed |
pubmed-article:20105326 | pubmed:affiliation | Department of Physiological Chemistry I, Biocenter, University of Würzburg, Würzburg, Germany. phch1@biozentrum.uni-wuerzburg.de. | lld:pubmed |
pubmed-article:20105326 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:20105326 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |