| pubmed-article:20067 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:20067 | lifeskim:mentions | umls-concept:C0031441 | lld:lifeskim |
| pubmed-article:20067 | lifeskim:mentions | umls-concept:C1280500 | lld:lifeskim |
| pubmed-article:20067 | lifeskim:mentions | umls-concept:C0243076 | lld:lifeskim |
| pubmed-article:20067 | lifeskim:mentions | umls-concept:C0332206 | lld:lifeskim |
| pubmed-article:20067 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:20067 | pubmed:dateCreated | 1977-10-31 | lld:pubmed |
| pubmed-article:20067 | pubmed:abstractText | The effect of beta-adrenoceptor antagonists on the irreversible alpha-adrenoceptor blockade produced by phenoxybenzamine was studied in dogs. The pressor effects of adrenaline were revived after the inhibition by the alpha-receptor block by (+/-) propranolol, (-) INPEA, (+/-) MJ 1999 and (+/-) butoxamine. The enantiomers (+) propranolol and (+) INPEA were ineffective in this regard. (+/-) Practolol also did not revive the pressor effect of the amines. The alpha-receptor mediated effect of the amines, in the nictitating membrana-receptor blockade. It is concluded that (1) blockade of the peripheral (beta-2) receptors is essential for the revival of the pressor effects, (2) local anesthetic effect of the beta-antagonists is not involved. Further work using a series of doses of agonists and antagonists of alpha-and beta-receptors is indicated to clarify the nature of this drug-interaction. | lld:pubmed |
| pubmed-article:20067 | pubmed:language | eng | lld:pubmed |
| pubmed-article:20067 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20067 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:20067 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20067 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20067 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20067 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20067 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20067 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:20067 | pubmed:month | May | lld:pubmed |
| pubmed-article:20067 | pubmed:issn | 0301-4533 | lld:pubmed |
| pubmed-article:20067 | pubmed:author | pubmed-author:SharmaP LPL | lld:pubmed |
| pubmed-article:20067 | pubmed:author | pubmed-author:Sankaranaraya... | lld:pubmed |
| pubmed-article:20067 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:20067 | pubmed:volume | 227 | lld:pubmed |
| pubmed-article:20067 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:20067 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:20067 | pubmed:pagination | 11-22 | lld:pubmed |
| pubmed-article:20067 | pubmed:dateRevised | 2003-11-14 | lld:pubmed |
| pubmed-article:20067 | pubmed:meshHeading | pubmed-meshheading:20067-An... | lld:pubmed |
| pubmed-article:20067 | pubmed:meshHeading | pubmed-meshheading:20067-Sp... | lld:pubmed |
| pubmed-article:20067 | pubmed:meshHeading | pubmed-meshheading:20067-He... | lld:pubmed |
| pubmed-article:20067 | pubmed:meshHeading | pubmed-meshheading:20067-Bl... | lld:pubmed |
| pubmed-article:20067 | pubmed:meshHeading | pubmed-meshheading:20067-Do... | lld:pubmed |
| pubmed-article:20067 | pubmed:meshHeading | pubmed-meshheading:20067-Ni... | lld:pubmed |
| pubmed-article:20067 | pubmed:meshHeading | pubmed-meshheading:20067-Ca... | lld:pubmed |
| pubmed-article:20067 | pubmed:meshHeading | pubmed-meshheading:20067-Fe... | lld:pubmed |
| pubmed-article:20067 | pubmed:meshHeading | pubmed-meshheading:20067-Ma... | lld:pubmed |
| pubmed-article:20067 | pubmed:meshHeading | pubmed-meshheading:20067-Mu... | lld:pubmed |
| pubmed-article:20067 | pubmed:meshHeading | pubmed-meshheading:20067-Ti... | lld:pubmed |
| pubmed-article:20067 | pubmed:meshHeading | pubmed-meshheading:20067-Ph... | lld:pubmed |
| pubmed-article:20067 | pubmed:meshHeading | pubmed-meshheading:20067-Mu... | lld:pubmed |
| pubmed-article:20067 | pubmed:meshHeading | pubmed-meshheading:20067-Ad... | lld:pubmed |
| pubmed-article:20067 | pubmed:meshHeading | pubmed-meshheading:20067-Dr... | lld:pubmed |
| pubmed-article:20067 | pubmed:meshHeading | pubmed-meshheading:20067-Re... | lld:pubmed |
| pubmed-article:20067 | pubmed:meshHeading | pubmed-meshheading:20067-Re... | lld:pubmed |
| pubmed-article:20067 | pubmed:year | 1977 | lld:pubmed |
| pubmed-article:20067 | pubmed:articleTitle | The effect of beta-adrenoceptor antagonists on the alpha-adrenoceptor blockade produced by phenoxybenzamine. | lld:pubmed |
| pubmed-article:20067 | pubmed:publicationType | Journal Article | lld:pubmed |
