| pubmed-article:20055680 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:20055680 | lifeskim:mentions | umls-concept:C0011923 | lld:lifeskim |
| pubmed-article:20055680 | lifeskim:mentions | umls-concept:C0475264 | lld:lifeskim |
| pubmed-article:20055680 | pubmed:dateCreated | 2010-4-6 | lld:pubmed |
| pubmed-article:20055680 | pubmed:abstractText | Superresolution imaging is a rapidly emerging new field of microscopy that dramatically improves the spatial resolution of light microscopy by over an order of magnitude (approximately 10-20-nm resolution), allowing biological processes to be described at the molecular scale. Here, we discuss a form of superresolution microscopy based on the controlled activation and sampling of sparse subsets of photoconvertible fluorescent molecules. In this single-molecule-based imaging approach, a wide variety of probes have proved valuable, ranging from genetically encodable photoactivatable fluorescent proteins to photoswitchable cyanine dyes. These have been used in diverse applications of superresolution imaging: from three-dimensional, multicolor molecule localization to tracking of nanometric structures and molecules in living cells. Single-molecule-based superresolution imaging thus offers exciting possibilities for obtaining molecular-scale information on biological events occurring at variable timescales. | lld:pubmed |
| pubmed-article:20055680 | pubmed:language | eng | lld:pubmed |
| pubmed-article:20055680 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20055680 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:20055680 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20055680 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:20055680 | pubmed:month | Mar | lld:pubmed |
| pubmed-article:20055680 | pubmed:issn | 0066-426X | lld:pubmed |
| pubmed-article:20055680 | pubmed:author | pubmed-author:DavidsonMicha... | lld:pubmed |
| pubmed-article:20055680 | pubmed:author | pubmed-author:Lippincott-Sc... | lld:pubmed |
| pubmed-article:20055680 | pubmed:author | pubmed-author:PattersonGeor... | lld:pubmed |
| pubmed-article:20055680 | pubmed:author | pubmed-author:ManleySuliana... | lld:pubmed |
| pubmed-article:20055680 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:20055680 | pubmed:volume | 61 | lld:pubmed |
| pubmed-article:20055680 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:20055680 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:20055680 | pubmed:pagination | 345-67 | lld:pubmed |
| pubmed-article:20055680 | pubmed:meshHeading | pubmed-meshheading:20055680... | lld:pubmed |
| pubmed-article:20055680 | pubmed:meshHeading | pubmed-meshheading:20055680... | lld:pubmed |
| pubmed-article:20055680 | pubmed:meshHeading | pubmed-meshheading:20055680... | lld:pubmed |
| pubmed-article:20055680 | pubmed:meshHeading | pubmed-meshheading:20055680... | lld:pubmed |
| pubmed-article:20055680 | pubmed:year | 2010 | lld:pubmed |
| pubmed-article:20055680 | pubmed:articleTitle | Superresolution imaging using single-molecule localization. | lld:pubmed |
| pubmed-article:20055680 | pubmed:affiliation | Biophotonics Section, National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, Bethesda, Maryland 20892, USA. | lld:pubmed |
| pubmed-article:20055680 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:20055680 | pubmed:publicationType | Review | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:20055680 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:20055680 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:20055680 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:20055680 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:20055680 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:20055680 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:20055680 | lld:pubmed |
