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pubmed-article:20028567pubmed:abstractTextLynch syndrome (LS) is associated with a high risk for colorectal cancer (CRC) and extracolonic malignancies, such as endometrial carcinoma (EC). The risk is dependent of the affected mismatch repair gene. The aim of the present study was to calculate the cumulative risk of LS related cancers in proven MLH1, MSH2 and MSH6 mutation carriers.lld:pubmed
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pubmed-article:20028567pubmed:articleTitleCancer risk in MLH1, MSH2 and MSH6 mutation carriers; different risk profiles may influence clinical management.lld:pubmed
pubmed-article:20028567pubmed:affiliationDepartment of Gastroenterology and Hepatology Erasmus MC University Medical Center, PO Box 2040, 3000 CA, Rotterdam, the Netherlands.lld:pubmed
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