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pubmed-article:19917065pubmed:abstractTextThe association between torcetrapib and its off-target effects on blood pressure suggested a possible class-specific effect. The effects of dalcetrapib (RO4607381/JTT-705) and torcetrapib on haemodynamics and the renin-angiotensin-aldosterone system (RAAS) were therefore assessed in a rat model.lld:pubmed
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pubmed-article:19917065pubmed:dateRevised2011-3-3lld:pubmed
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pubmed-article:19917065pubmed:articleTitleDalcetrapib: no off-target toxicity on blood pressure or on genes related to the renin-angiotensin-aldosterone system in rats.lld:pubmed
pubmed-article:19917065pubmed:affiliationDepartment of Vascular Medicine, Academic Medical Center, Amsterdam, The Netherlands. e.s.stroes@amc.uva.nllld:pubmed
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