| pubmed-article:19906812 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:19906812 | lifeskim:mentions | umls-concept:C0001675 | lld:lifeskim |
| pubmed-article:19906812 | lifeskim:mentions | umls-concept:C0596227 | lld:lifeskim |
| pubmed-article:19906812 | lifeskim:mentions | umls-concept:C0036581 | lld:lifeskim |
| pubmed-article:19906812 | lifeskim:mentions | umls-concept:C0449438 | lld:lifeskim |
| pubmed-article:19906812 | lifeskim:mentions | umls-concept:C0332281 | lld:lifeskim |
| pubmed-article:19906812 | lifeskim:mentions | umls-concept:C1979963 | lld:lifeskim |
| pubmed-article:19906812 | lifeskim:mentions | umls-concept:C2003903 | lld:lifeskim |
| pubmed-article:19906812 | lifeskim:mentions | umls-concept:C0596192 | lld:lifeskim |
| pubmed-article:19906812 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:19906812 | pubmed:dateCreated | 2009-12-21 | lld:pubmed |
| pubmed-article:19906812 | pubmed:abstractText | Recent findings have raised concern about possible associations of high selenium exposure with diabetes and hyperlipidemia in the US, a population with high selenium status. In the UK, a population with lower selenium status, there is little data on the association of selenium status with cardio-metabolic risk factors in the general population. We examined the association of plasma selenium concentration with blood lipids in a nationally representative sample of British adults. A cross-sectional study was conducted among 1042 white participants (aged 19-64 y) in the 2000-2001 UK National Diet and Nutrition Survey. Plasma selenium was measured by inductively coupled-plasma mass spectrometry. Total and HDL cholesterol were measured in nonfasting plasma samples. Mean plasma selenium concentration was 1.10 +/- 0.19 micromol/L. The multivariate adjusted differences between the highest (> or =1.20 micromol/L) and lowest (<0.98 micromol/L) quartiles of plasma selenium were 0.39 (95% CI 0.18, 0.60) mmol/L for total cholesterol, 0.38 (0.17, 0.59) for non-HDL cholesterol, and 0.01 (-0.05, 0.07) for HDL cholesterol. Higher plasma selenium (i.e., > or =1.20 micromol/L) was associated with increased total and non-HDL cholesterol levels but not with HDL in the UK adult population. These findings raise additional concern about potential adverse cardio-metabolic effects of high selenium status. Randomized and mechanistic evidence is necessary to assess causality and to evaluate the impact of this association on cardiovascular risk. | lld:pubmed |
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| pubmed-article:19906812 | pubmed:language | eng | lld:pubmed |
| pubmed-article:19906812 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19906812 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:19906812 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19906812 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19906812 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:19906812 | pubmed:month | Jan | lld:pubmed |
| pubmed-article:19906812 | pubmed:issn | 1541-6100 | lld:pubmed |
| pubmed-article:19906812 | pubmed:author | pubmed-author:OrdovasJose... | lld:pubmed |
| pubmed-article:19906812 | pubmed:author | pubmed-author:CappuccioFran... | lld:pubmed |
| pubmed-article:19906812 | pubmed:author | pubmed-author:GuallarEliseo... | lld:pubmed |
| pubmed-article:19906812 | pubmed:author | pubmed-author:StrangesSaver... | lld:pubmed |
| pubmed-article:19906812 | pubmed:author | pubmed-author:RaymanMargare... | lld:pubmed |
| pubmed-article:19906812 | pubmed:author | pubmed-author:ChenJiJ | lld:pubmed |
| pubmed-article:19906812 | pubmed:author | pubmed-author:Navas-AcienAn... | lld:pubmed |
| pubmed-article:19906812 | pubmed:author | pubmed-author:LaclaustraMar... | lld:pubmed |
| pubmed-article:19906812 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:19906812 | pubmed:volume | 140 | lld:pubmed |
| pubmed-article:19906812 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:19906812 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:19906812 | pubmed:pagination | 81-7 | lld:pubmed |
| pubmed-article:19906812 | pubmed:dateRevised | 2011-7-19 | lld:pubmed |
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| pubmed-article:19906812 | pubmed:year | 2010 | lld:pubmed |
