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pubmed-article:19860571pubmed:abstractTextSuccessful photodynamic therapy (PDT) requires high production of radical ions and singlet oxygen to kill target cells. However, PDT also induces angiogenesis through production of vascular endothelial growth factor (VEGF), which promotes cell regrowth and vascularization. In this study, we evaluated the importance of oxygen in PDT by measuring oxygen consumption, photosensitizer bleaching, and reactive oxygen species (ROS) production in the culture medium, and VEGF secretion either during or after PDT treatment using mouse Lewis lung carcinoma (LLC) cells.lld:pubmed
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pubmed-article:19860571pubmed:articleTitleEvaluation of oxygen consumption of culture medium and in vitro photodynamic effect of talaporfin sodium in lung tumor cells.lld:pubmed
pubmed-article:19860571pubmed:affiliationDivision of Sustainable Energy and Environmental Engineering, Graduate School of Engineering, Osaka University, Osaka, Japan.lld:pubmed
pubmed-article:19860571pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:19860571pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed