| pubmed-article:1985195 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:1985195 | lifeskim:mentions | umls-concept:C0035691 | lld:lifeskim |
| pubmed-article:1985195 | lifeskim:mentions | umls-concept:C0043393 | lld:lifeskim |
| pubmed-article:1985195 | lifeskim:mentions | umls-concept:C0035693 | lld:lifeskim |
| pubmed-article:1985195 | lifeskim:mentions | umls-concept:C0042736 | lld:lifeskim |
| pubmed-article:1985195 | lifeskim:mentions | umls-concept:C0017262 | lld:lifeskim |
| pubmed-article:1985195 | lifeskim:mentions | umls-concept:C0598312 | lld:lifeskim |
| pubmed-article:1985195 | lifeskim:mentions | umls-concept:C0678921 | lld:lifeskim |
| pubmed-article:1985195 | lifeskim:mentions | umls-concept:C2911684 | lld:lifeskim |
| pubmed-article:1985195 | lifeskim:mentions | umls-concept:C0185117 | lld:lifeskim |
| pubmed-article:1985195 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:1985195 | pubmed:dateCreated | 1991-2-7 | lld:pubmed |
| pubmed-article:1985195 | pubmed:abstractText | The plus strand of the L-A double-stranded RNA virus of Saccharomyces cerevisiae has two large open reading frames, ORF1, which encodes the major coat protein, and ORF2, which encodes a single-stranded RNA-binding protein having a sequence diagnostic of viral RNA-dependent RNA polymerases. ORF2 is expressed only as a Gag-Pol-type fusion protein with ORF1. We have constructed a plasmid which expresses these proteins from the yeast PGK1 promoter. We show that this plasmid can support the replication of the killer toxin-encoding M1 satellite virus in the absence of an L-A double-stranded RNA helper virus itself. This requires ORF2 expression, providing a potential in vivo assay for the RNA polymerase and single-stranded RNA-binding activities of the fusion protein determined by ORF2. ORF1 expression, like a host ski- mutation, can suppress the usual requirement of M1 for the MAK11, MAK18, and MAK27 genes and allow a defective L-A (L-A-E) to support M1 replication. These results suggest that expression of ORF1 from the vector makes the cell a ski- phenocopy. Indeed, expression of ORF1 in a wild-type killer makes it a superkiller, suggesting that a target of the SKI antiviral system may be the major coat protein. | lld:pubmed |
| pubmed-article:1985195 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1985195 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1985195 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1985195 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1985195 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1985195 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1985195 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1985195 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1985195 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1985195 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1985195 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1985195 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1985195 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1985195 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1985195 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1985195 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1985195 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1985195 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1985195 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1985195 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1985195 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1985195 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1985195 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1985195 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1985195 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1985195 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1985195 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1985195 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1985195 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1985195 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1985195 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1985195 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1985195 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1985195 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1985195 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1985195 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1985195 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1985195 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1985195 | pubmed:language | eng | lld:pubmed |
| pubmed-article:1985195 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1985195 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:1985195 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1985195 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1985195 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:1985195 | pubmed:month | Jan | lld:pubmed |
| pubmed-article:1985195 | pubmed:issn | 0022-538X | lld:pubmed |
| pubmed-article:1985195 | pubmed:author | pubmed-author:IchoTT | lld:pubmed |
| pubmed-article:1985195 | pubmed:author | pubmed-author:WicknerR BRB | lld:pubmed |
| pubmed-article:1985195 | pubmed:author | pubmed-author:FujimuraTT | lld:pubmed |
| pubmed-article:1985195 | pubmed:author | pubmed-author:WidnerW RWR | lld:pubmed |
| pubmed-article:1985195 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:1985195 | pubmed:volume | 65 | lld:pubmed |
| pubmed-article:1985195 | pubmed:geneSymbol | ski | lld:pubmed |
| pubmed-article:1985195 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:1985195 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:1985195 | pubmed:pagination | 155-61 | lld:pubmed |
| pubmed-article:1985195 | pubmed:dateRevised | 2010-9-9 | lld:pubmed |
| pubmed-article:1985195 | pubmed:meshHeading | pubmed-meshheading:1985195-... | lld:pubmed |
| pubmed-article:1985195 | pubmed:meshHeading | pubmed-meshheading:1985195-... | lld:pubmed |
| pubmed-article:1985195 | pubmed:meshHeading | pubmed-meshheading:1985195-... | lld:pubmed |
| pubmed-article:1985195 | pubmed:meshHeading | pubmed-meshheading:1985195-... | lld:pubmed |
| pubmed-article:1985195 | pubmed:meshHeading | pubmed-meshheading:1985195-... | lld:pubmed |
| pubmed-article:1985195 | pubmed:meshHeading | pubmed-meshheading:1985195-... | lld:pubmed |
| pubmed-article:1985195 | pubmed:meshHeading | pubmed-meshheading:1985195-... | lld:pubmed |
| pubmed-article:1985195 | pubmed:meshHeading | pubmed-meshheading:1985195-... | lld:pubmed |
| pubmed-article:1985195 | pubmed:meshHeading | pubmed-meshheading:1985195-... | lld:pubmed |
| pubmed-article:1985195 | pubmed:meshHeading | pubmed-meshheading:1985195-... | lld:pubmed |
| pubmed-article:1985195 | pubmed:meshHeading | pubmed-meshheading:1985195-... | lld:pubmed |
| pubmed-article:1985195 | pubmed:meshHeading | pubmed-meshheading:1985195-... | lld:pubmed |
| pubmed-article:1985195 | pubmed:meshHeading | pubmed-meshheading:1985195-... | lld:pubmed |
| pubmed-article:1985195 | pubmed:meshHeading | pubmed-meshheading:1985195-... | lld:pubmed |
| pubmed-article:1985195 | pubmed:year | 1991 | lld:pubmed |
| pubmed-article:1985195 | pubmed:articleTitle | Expression of yeast L-A double-stranded RNA virus proteins produces derepressed replication: a ski- phenocopy. | lld:pubmed |
| pubmed-article:1985195 | pubmed:affiliation | Section on the Genetics of Simple Eukaryotes, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, Maryland 20892. | lld:pubmed |
| pubmed-article:1985195 | pubmed:publicationType | Journal Article | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1985195 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1985195 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1985195 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1985195 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1985195 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1985195 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1985195 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1985195 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1985195 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1985195 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1985195 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1985195 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1985195 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1985195 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1985195 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1985195 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1985195 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1985195 | lld:pubmed |
