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pubmed-article:19794929pubmed:dateCreated2009-10-1lld:pubmed
pubmed-article:19794929pubmed:abstractTextd-psicose is one of the rare sugars present in small quantities in commercial carbohydrates and agricultural products. In this study, we investigated the effects of d-psicose on the activities of alpha-amylases and alpha-glucosidases in vitro, and evaluated the effects of d-psicose on the in vivo postprandial glycemic response using rats. In the in vitro study, d-psicose potently inhibited the intestinal sucrase and maltase, however, slightly inhibited the intestinal and salivary alpha-amylase activities. Male Wistar rats (6 months old) were administrated 2 g/kg of sucrose, maltose or soluble starch together with 0.2 g/kg of d-psicose or d-fructose. The d-psicose significantly inhibited the increment of plasma glucose concentration induced by sucrose or maltose. The starch-induced glycemic response tended to be suppressed by d-psicose, however the suppression was not significant. These results suggest that d-psicose inhibits intestinal sucrase and maltase activities and suppresses the plasma glucose increase the normally occurs after sucrose and maltose ingestion. Thus, d-psicose may be useful in preventing postprandial hyperglycemia in diabetic patients when foods containing sucrose and maltose are ingested.lld:pubmed
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pubmed-article:19794929pubmed:languageenglld:pubmed
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pubmed-article:19794929pubmed:statusPubMed-not-MEDLINElld:pubmed
pubmed-article:19794929pubmed:monthSeplld:pubmed
pubmed-article:19794929pubmed:issn0912-0009lld:pubmed
pubmed-article:19794929pubmed:authorpubmed-author:MatsuoTatsuhi...lld:pubmed
pubmed-article:19794929pubmed:authorpubmed-author:IzumoriKenKlld:pubmed
pubmed-article:19794929pubmed:issnTypePrintlld:pubmed
pubmed-article:19794929pubmed:volume45lld:pubmed
pubmed-article:19794929pubmed:ownerNLMlld:pubmed
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pubmed-article:19794929pubmed:pagination202-6lld:pubmed
pubmed-article:19794929pubmed:year2009lld:pubmed
pubmed-article:19794929pubmed:articleTitled-Psicose Inhibits Intestinal alpha-Glucosidase and Suppresses the Glycemic Response after Ingestion of Carbohydrates in Rats.lld:pubmed
pubmed-article:19794929pubmed:affiliationFaculty of Agriculture, Kagawa University, Ikenobe 2393, Miki-cho, Kita-gun, Kagawa 761-0795, Japan.lld:pubmed
pubmed-article:19794929pubmed:publicationTypeJournal Articlelld:pubmed
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