| pubmed-article:19783436 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:19783436 | lifeskim:mentions | umls-concept:C0033684 | lld:lifeskim |
| pubmed-article:19783436 | lifeskim:mentions | umls-concept:C0600500 | lld:lifeskim |
| pubmed-article:19783436 | lifeskim:mentions | umls-concept:C0021467 | lld:lifeskim |
| pubmed-article:19783436 | lifeskim:mentions | umls-concept:C1415504 | lld:lifeskim |
| pubmed-article:19783436 | lifeskim:mentions | umls-concept:C0596988 | lld:lifeskim |
| pubmed-article:19783436 | lifeskim:mentions | umls-concept:C1660642 | lld:lifeskim |
| pubmed-article:19783436 | lifeskim:mentions | umls-concept:C0021469 | lld:lifeskim |
| pubmed-article:19783436 | lifeskim:mentions | umls-concept:C0332256 | lld:lifeskim |
| pubmed-article:19783436 | lifeskim:mentions | umls-concept:C0303920 | lld:lifeskim |
| pubmed-article:19783436 | lifeskim:mentions | umls-concept:C0599219 | lld:lifeskim |
| pubmed-article:19783436 | lifeskim:mentions | umls-concept:C0597101 | lld:lifeskim |
| pubmed-article:19783436 | pubmed:issue | 21 | lld:pubmed |
| pubmed-article:19783436 | pubmed:dateCreated | 2009-10-12 | lld:pubmed |
| pubmed-article:19783436 | pubmed:abstractText | Peptide nucleic acid (PNA) is a successful DNA/RNA mimic. A major challenge for research is to invent chemically modified PNAs that retain the favorable properties of the parent compound while improving biological recognition. Here, we test modified PNAs containing [bis-o-(aminoethoxy)phenyl]pyrrolocytosine bases designed to engage guanine with an additional hydrogen bond. We observe elevated melting temperatures, localization to cellular compartments, and allele-selective inhibition of mutant huntingtin protein expression. | lld:pubmed |
| pubmed-article:19783436 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19783436 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19783436 | pubmed:language | eng | lld:pubmed |
| pubmed-article:19783436 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19783436 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:19783436 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19783436 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19783436 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19783436 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19783436 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19783436 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19783436 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19783436 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19783436 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19783436 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:19783436 | pubmed:month | Nov | lld:pubmed |
| pubmed-article:19783436 | pubmed:issn | 1464-3405 | lld:pubmed |
| pubmed-article:19783436 | pubmed:author | pubmed-author:CoreyDavid... | lld:pubmed |
| pubmed-article:19783436 | pubmed:author | pubmed-author:HuJiaxinJ | lld:pubmed |
| pubmed-article:19783436 | pubmed:author | pubmed-author:HudsonRobert... | lld:pubmed |
| pubmed-article:19783436 | pubmed:author | pubmed-author:DoddDavid WDW | lld:pubmed |
| pubmed-article:19783436 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:19783436 | pubmed:day | 1 | lld:pubmed |
| pubmed-article:19783436 | pubmed:volume | 19 | lld:pubmed |
| pubmed-article:19783436 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:19783436 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:19783436 | pubmed:pagination | 6181-4 | lld:pubmed |
| pubmed-article:19783436 | pubmed:dateRevised | 2011-9-26 | lld:pubmed |
| pubmed-article:19783436 | pubmed:meshHeading | pubmed-meshheading:19783436... | lld:pubmed |
| pubmed-article:19783436 | pubmed:meshHeading | pubmed-meshheading:19783436... | lld:pubmed |
| pubmed-article:19783436 | pubmed:meshHeading | pubmed-meshheading:19783436... | lld:pubmed |
| pubmed-article:19783436 | pubmed:meshHeading | pubmed-meshheading:19783436... | lld:pubmed |
| pubmed-article:19783436 | pubmed:meshHeading | pubmed-meshheading:19783436... | lld:pubmed |
| pubmed-article:19783436 | pubmed:meshHeading | pubmed-meshheading:19783436... | lld:pubmed |
| pubmed-article:19783436 | pubmed:meshHeading | pubmed-meshheading:19783436... | lld:pubmed |
| pubmed-article:19783436 | pubmed:meshHeading | pubmed-meshheading:19783436... | lld:pubmed |
| pubmed-article:19783436 | pubmed:meshHeading | pubmed-meshheading:19783436... | lld:pubmed |
| pubmed-article:19783436 | pubmed:meshHeading | pubmed-meshheading:19783436... | lld:pubmed |
| pubmed-article:19783436 | pubmed:meshHeading | pubmed-meshheading:19783436... | lld:pubmed |
| pubmed-article:19783436 | pubmed:meshHeading | pubmed-meshheading:19783436... | lld:pubmed |
| pubmed-article:19783436 | pubmed:meshHeading | pubmed-meshheading:19783436... | lld:pubmed |
| pubmed-article:19783436 | pubmed:year | 2009 | lld:pubmed |
| pubmed-article:19783436 | pubmed:articleTitle | Cellular localization and allele-selective inhibition of mutant huntingtin protein by peptide nucleic acid oligomers containing the fluorescent nucleobase [bis-o-(aminoethoxy)phenyl]pyrrolocytosine. | lld:pubmed |
| pubmed-article:19783436 | pubmed:affiliation | Department of Pharmacology, UT Southwestern Medical Center at Dallas, Dallas, 6001 Forest Park Road, TX 75390, USA. | lld:pubmed |
| pubmed-article:19783436 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:19783436 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| pubmed-article:19783436 | pubmed:publicationType | Research Support, N.I.H., Extramural | lld:pubmed |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | pubmed-article:19783436 | lld:chembl |
