| pubmed-article:19771163 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:19771163 | lifeskim:mentions | umls-concept:C0007634 | lld:lifeskim |
| pubmed-article:19771163 | lifeskim:mentions | umls-concept:C1956385 | lld:lifeskim |
| pubmed-article:19771163 | lifeskim:mentions | umls-concept:C0003342 | lld:lifeskim |
| pubmed-article:19771163 | lifeskim:mentions | umls-concept:C0332157 | lld:lifeskim |
| pubmed-article:19771163 | pubmed:issue | 9 | lld:pubmed |
| pubmed-article:19771163 | pubmed:dateCreated | 2009-9-22 | lld:pubmed |
| pubmed-article:19771163 | pubmed:abstractText | Among the different subsets of dendritic cells (DC), plasmacytoid dendritic cells (PDC) play a unique role in secreting large amounts of type I interferons upon viral stimulation, but their efficiency as antigen-presenting cells has not been completely characterized. We show here, by flow cytometry, with human primary blood PDC and with a PDC cell line, that PDC display poor endocytic capacity for soluble or cellular antigens when compared to monocyte-derived myeloid DC. However, immature PDC efficiently take up cellular material from live influenza-exposed cells, subsequently mature and cross-present viral antigens very efficiently to specific CD8+ T cells. Therefore, during viral infection PDC not only secrete immunomodulatory cytokines, but also recognize infected cells and function as antigen cross-presenting cells to trigger the anti-viral immune response. | lld:pubmed |
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| pubmed-article:19771163 | pubmed:language | eng | lld:pubmed |
| pubmed-article:19771163 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19771163 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:19771163 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:19771163 | pubmed:issn | 1932-6203 | lld:pubmed |
| pubmed-article:19771163 | pubmed:author | pubmed-author:ChaperotLaure... | lld:pubmed |
| pubmed-article:19771163 | pubmed:author | pubmed-author:ManchesOlivie... | lld:pubmed |
| pubmed-article:19771163 | pubmed:author | pubmed-author:MolensJean-Pa... | lld:pubmed |
| pubmed-article:19771163 | pubmed:author | pubmed-author:PlumasJoëlJ | lld:pubmed |
| pubmed-article:19771163 | pubmed:author | pubmed-author:LuiGabrielleG | lld:pubmed |
| pubmed-article:19771163 | pubmed:author | pubmed-author:AngelJuliette... | lld:pubmed |
| pubmed-article:19771163 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:19771163 | pubmed:volume | 4 | lld:pubmed |
| pubmed-article:19771163 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:19771163 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:19771163 | pubmed:pagination | e7111 | lld:pubmed |
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| pubmed-article:19771163 | pubmed:meshHeading | pubmed-meshheading:19771163... | lld:pubmed |
| pubmed-article:19771163 | pubmed:meshHeading | pubmed-meshheading:19771163... | lld:pubmed |
| pubmed-article:19771163 | pubmed:meshHeading | pubmed-meshheading:19771163... | lld:pubmed |
| pubmed-article:19771163 | pubmed:meshHeading | pubmed-meshheading:19771163... | lld:pubmed |
| pubmed-article:19771163 | pubmed:meshHeading | pubmed-meshheading:19771163... | lld:pubmed |
| pubmed-article:19771163 | pubmed:meshHeading | pubmed-meshheading:19771163... | lld:pubmed |
| pubmed-article:19771163 | pubmed:meshHeading | pubmed-meshheading:19771163... | lld:pubmed |
| pubmed-article:19771163 | pubmed:meshHeading | pubmed-meshheading:19771163... | lld:pubmed |
| pubmed-article:19771163 | pubmed:year | 2009 | lld:pubmed |
| pubmed-article:19771163 | pubmed:articleTitle | Plasmacytoid dendritic cells capture and cross-present viral antigens from influenza-virus exposed cells. | lld:pubmed |
| pubmed-article:19771163 | pubmed:affiliation | Université Joseph Fourier, Grenoble, France. | lld:pubmed |
| pubmed-article:19771163 | pubmed:publicationType | Journal Article | lld:pubmed |
