Hypogonadism frequently occurs in men with type 2 diabetes mellitus (T2DM), while the role of glycemic control and visceral obesity is still unclear. This study aimed to assess the Leydig cell function, including the new sensitive marker insulin-like factor 3 (INSL3), in T2DM patients without overt hypogonadism and the influence of either glycemic control or visceral adiposity.
Peripheral insulin-like factor 3 concentrations are reduced in men with type 2 diabetes mellitus: effect of glycemic control and visceral adiposity on Leydig cell function.
Endocrinology and Diabetology Unit, Department of Medical-Surgical Sciences, Università degli Studi di Milano, IRCCS Policlinico San Donato, Via Morandi 30, 20097 San Donato Milanese, Milano, Italy.
