pubmed-article:19729843 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:19729843 | lifeskim:mentions | umls-concept:C0038411 | lld:lifeskim |
pubmed-article:19729843 | lifeskim:mentions | umls-concept:C1521991 | lld:lifeskim |
pubmed-article:19729843 | lifeskim:mentions | umls-concept:C0936012 | lld:lifeskim |
pubmed-article:19729843 | pubmed:issue | 9 | lld:pubmed |
pubmed-article:19729843 | pubmed:dateCreated | 2009-9-4 | lld:pubmed |
pubmed-article:19729843 | pubmed:abstractText | Molecular pathogenomic analysis of the human bacterial pathogen group A Streptococcus has been conducted for a decade. Much has been learned as a consequence of the confluence of low-cost DNA sequencing, microarray technology, high-throughput proteomics, and enhanced bioinformatics. These technical advances, coupled with the availability of unique bacterial strain collections, have facilitated a systems biology investigative strategy designed to enhance and accelerate our understanding of disease processes. Here, we provide examples of the progress made by exploiting an integrated genome-wide research platform to gain new insight into molecular pathogenesis. The studies have provided many new avenues for basic and translational research. | lld:pubmed |
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