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pubmed-article:19699471pubmed:abstractTextEndophenotypes are simple biological aspects of a disease that can be observed in unaffected relatives at a higher rate than in the general population; an "autism endophenotype" justifies the observation that a mild reduction in ideational fluency and nonverbal generativity might be observed in healthy, unaffected relatives of children with autism. Because it is becoming apparent that autism is associated with given alleles encoding within the human leukocyte antigens region, a region of pivotal importance in immunity, we examined whether the "autism endophenotype" would extend its effects on the immune system.lld:pubmed
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pubmed-article:19699471pubmed:articleTitleAn autistic endophenotype results in complex immune dysfunction in healthy siblings of autistic children.lld:pubmed
pubmed-article:19699471pubmed:affiliationLaboratory of Molecular Medicine and Biotechnology, Don C. Gnocchi ONLUS Foundation IRCCS-S.M. Nascente, Italy. msaresella@dongnocchi.itlld:pubmed
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