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pubmed-article:19648166pubmed:abstractTextC-type lectin-like molecule-1 is a transmembrane receptor expressed on myeloid cells, acute myeloid leukemia blasts and leukemic stem cells. To validate the potential of this receptor as a therapeutic target in acute myeloid leukemia, we generated a series of monoclonal antibodies against the extracellular domain of C-type lectin-like molecule-1 and used them to extend the expression profile analysis of acute myeloid leukemia cells and to select cytotoxic monoclonal antibodies against acute myeloid leukemia cells in preclinical models.lld:pubmed
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pubmed-article:19648166pubmed:articleTitleTargeting C-type lectin-like molecule-1 for antibody-mediated immunotherapy in acute myeloid leukemia.lld:pubmed
pubmed-article:19648166pubmed:affiliationDepartment of Clinical Pathology, Cleveland Clinic, Cleveland, OH, USA.lld:pubmed
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