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pubmed-article:19641174pubmed:abstractTextEphA2 is overexpressed in many types of human cancer but is absent or expressed at low levels in normal epithelial tissues. We investigated whether a novel immunoconjugate containing an anti-EphA2 monoclonal antibody (1C1) linked to a chemotherapeutic agent (monomethyl auristatin phenylalanine [MMAF]) through a noncleavable linker maleimidocaproyl (mc) had antitumor activity against ovarian cancer cell lines and tumor models.lld:pubmed
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pubmed-article:19641174pubmed:articleTitleEphA2 immunoconjugate as molecularly targeted chemotherapy for ovarian carcinoma.lld:pubmed
pubmed-article:19641174pubmed:affiliationDepartment of Gynecologic Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.lld:pubmed
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