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pubmed-article:1963255pubmed:abstractTextDisturbed function of the hypothalamic-pituitary axis at adrenal and thyroid levels was found during an episode of hypersomnia in the idiopathic recurring hypersomnia syndrome. These endocrinological abnormalities, abolished ACTH and cortisol responses to insulin-induced hypoglycemia and absent TSH response to TRH, normalised thereafter in the symptom-free interval. These data support the hypothesis that Kleine-Levin syndrome is related to an intermittent hypothalamic dysfunction.lld:pubmed
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pubmed-article:1963255pubmed:articleTitleDisturbed hypothalamic-pituitary axis in idiopathic recurring hypersomnia syndrome.lld:pubmed
pubmed-article:1963255pubmed:affiliationDepartment of Neurology, Hospital Ramón y Cajal, Madrid, Spain.lld:pubmed
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