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pubmed-article:19559558pubmed:abstractTextThe purpose of this study was to compare observer interpreted steady-state coherent coronal images and gadolinium-enhanced axial images in terms of the detection and grading of esophageal varices. Magnetic resonance imaging (MRI) and gastrointestinal endoscopy were performed within 2 weeks in 90 patients with chronic liver damage, including 55 with untreated esophageal varices, for periodic screening purposes. Two blinded readers retrospectively reviewed T1- and T2-weighted images with gadolinium-enhanced (gadolinium image set) and steady-state coherent (coherent image set) images. Sensitivity for the detection of esophageal varices was higher (P<.001) in the gadolinium image set (76%) than in the coherent image set (35%); on the other hand, specificity was higher (P<.001) in the coherent image set (91%) than in the gadolinium image set (66%). Furthermore, area under the ROC curve was higher for the gadolinium image set (Az=0.823) than the coherent image set (Az=0.761) (P=.48). Moderate and weak positive correlations with endoscopic grades were found for the gadolinium image (r=0.48, P<.01) and coherent image sets (r=0.34, P=.018). The addition of steady-state coherent imaging to the current routine liver imaging protocol did not improve the detection or grading of esophageal varices, whereas gadolinium-enhanced imaging was found to be potentially valuable. Nevertheless, endoscopy was confirmed to be mandatory in patients with esophageal varices suspected by MRI of the liver.lld:pubmed
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pubmed-article:19559558pubmed:authorpubmed-author:KanematsuMasa...lld:pubmed
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pubmed-article:19559558pubmed:authorpubmed-author:GoshimaSatosh...lld:pubmed
pubmed-article:19559558pubmed:authorpubmed-author:TsugeYusukeYlld:pubmed
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pubmed-article:19559558pubmed:volume27lld:pubmed
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pubmed-article:19559558pubmed:year2009lld:pubmed
pubmed-article:19559558pubmed:articleTitleDetection and grading for esophageal varices in patients with chronic liver damage: comparison of gadolinium-enhanced and unenhanced steady-state coherent MR images.lld:pubmed
pubmed-article:19559558pubmed:affiliationDepartment of Radiology, Gifu University School of Medicine, 1-1 Yanagido, Gifu 501-1193, Japan.lld:pubmed
pubmed-article:19559558pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:19559558pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed