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pubmed-article:19481025pubmed:abstractTextThe serious shortage of organs for transplantation, especially lungs, has drawn increasing attention to donation after cardiac death and protection of organs against warm ischemic injury. Atrial natriuretic peptide (ANP) activates guanylate cyclase receptors and increases cyclic guanosine monophosphate (cGMP) levels, which decrease in the lung during ischemia. In this study we investigated the effect on lung ischemia-reperfusion injury of administering synthetic ANP (carperitide) at the onset of reperfusion after warm ischemia.lld:pubmed
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pubmed-article:19481025pubmed:articleTitlePost-ischemic infusion of atrial natriuretic peptide attenuates warm ischemia-reperfusion injury in rat lung.lld:pubmed
pubmed-article:19481025pubmed:affiliationDepartment of Thoracic Surgery, Graduate School of Medicine, Kyoto University, 54 Shogoin, Kawahara-cho, Sakyo-ku, Kyoto, Japan.lld:pubmed
pubmed-article:19481025pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:19481025pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed