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pubmed-article:19473545pubmed:abstractTextSchizophrenia is a severe, chronic, and costly illness that adversely impacts patients' lives and health care payer budgets. Cost comparisons of treatment regimens are, therefore, important to health care payers and researchers. Pre-Post analyses ("mirror-image"), where outcomes prior to a medication switch are compared to outcomes post-switch, are commonly used in such research. However, medication changes often occur during a costly crisis event. Patients may relapse, be hospitalized, have a medication change, and then spend a period of time with intense use of costly resources (post-medication switch). While many advantages and disadvantages of Pre-Post methodology have been discussed, issues regarding the attributability of costs incurred around the time of medication switching have not been fully investigated.lld:pubmed
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pubmed-article:19473545pubmed:statusPubMed-not-MEDLINElld:pubmed
pubmed-article:19473545pubmed:issn1478-7547lld:pubmed
pubmed-article:19473545pubmed:authorpubmed-author:FariesDouglas...lld:pubmed
pubmed-article:19473545pubmed:authorpubmed-author:Ascher-Svanum...lld:pubmed
pubmed-article:19473545pubmed:authorpubmed-author:NyhuisAllen...lld:pubmed
pubmed-article:19473545pubmed:issnTypeElectroniclld:pubmed
pubmed-article:19473545pubmed:volume7lld:pubmed
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pubmed-article:19473545pubmed:pagination11lld:pubmed
pubmed-article:19473545pubmed:year2009lld:pubmed
pubmed-article:19473545pubmed:articleTitleMethodological issues in assessing changes in costs pre- and post-medication switch: a schizophrenia study example.lld:pubmed
pubmed-article:19473545pubmed:affiliationLilly USA, LLC, Indianapolis, Indiana, USA. d.faries@lilly.comlld:pubmed
pubmed-article:19473545pubmed:publicationTypeJournal Articlelld:pubmed