| pubmed-article:19306875 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:19306875 | lifeskim:mentions | umls-concept:C1622501 | lld:lifeskim |
| pubmed-article:19306875 | lifeskim:mentions | umls-concept:C1145667 | lld:lifeskim |
| pubmed-article:19306875 | lifeskim:mentions | umls-concept:C0851285 | lld:lifeskim |
| pubmed-article:19306875 | lifeskim:mentions | umls-concept:C0213666 | lld:lifeskim |
| pubmed-article:19306875 | lifeskim:mentions | umls-concept:C1136119 | lld:lifeskim |
| pubmed-article:19306875 | pubmed:issue | 8 | lld:pubmed |
| pubmed-article:19306875 | pubmed:dateCreated | 2009-4-13 | lld:pubmed |
| pubmed-article:19306875 | pubmed:abstractText | Ephrins and Eph receptors have key roles in regulation of cell migration during development. We found that the RacGAP beta2-chimaerin (chimerin) bound to EphA2 and EphA4 and inactivated Rac1 in response to ephrinA1 stimulation. EphA4 bound to beta2-chimaerin through its kinase domain and promoted binding of Rac1 to beta2-chimaerin. In addition, knockdown of endogenous beta2-chimaerin blocked ephrinA1-induced suppression of cell migration. These results suggest that beta2-chimaerin is activated by EphA receptors and mediates the EphA receptor-dependent regulation of cell migration. | lld:pubmed |
| pubmed-article:19306875 | pubmed:language | eng | lld:pubmed |
| pubmed-article:19306875 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19306875 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:19306875 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19306875 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19306875 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19306875 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19306875 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:19306875 | pubmed:month | Apr | lld:pubmed |
| pubmed-article:19306875 | pubmed:issn | 1873-3468 | lld:pubmed |
| pubmed-article:19306875 | pubmed:author | pubmed-author:NegishiManabu... | lld:pubmed |
| pubmed-article:19306875 | pubmed:author | pubmed-author:IwasatoTakuji... | lld:pubmed |
| pubmed-article:19306875 | pubmed:author | pubmed-author:KatohHironori... | lld:pubmed |
| pubmed-article:19306875 | pubmed:author | pubmed-author:TakeuchiShing... | lld:pubmed |
| pubmed-article:19306875 | pubmed:author | pubmed-author:YamakiNaoN | lld:pubmed |
| pubmed-article:19306875 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:19306875 | pubmed:day | 17 | lld:pubmed |
| pubmed-article:19306875 | pubmed:volume | 583 | lld:pubmed |
| pubmed-article:19306875 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:19306875 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:19306875 | pubmed:pagination | 1237-42 | lld:pubmed |
| pubmed-article:19306875 | pubmed:dateRevised | 2009-11-19 | lld:pubmed |
| pubmed-article:19306875 | pubmed:meshHeading | pubmed-meshheading:19306875... | lld:pubmed |
| pubmed-article:19306875 | pubmed:meshHeading | pubmed-meshheading:19306875... | lld:pubmed |
| pubmed-article:19306875 | pubmed:meshHeading | pubmed-meshheading:19306875... | lld:pubmed |
| pubmed-article:19306875 | pubmed:meshHeading | pubmed-meshheading:19306875... | lld:pubmed |
| pubmed-article:19306875 | pubmed:meshHeading | pubmed-meshheading:19306875... | lld:pubmed |
| pubmed-article:19306875 | pubmed:meshHeading | pubmed-meshheading:19306875... | lld:pubmed |
| pubmed-article:19306875 | pubmed:meshHeading | pubmed-meshheading:19306875... | lld:pubmed |
| pubmed-article:19306875 | pubmed:meshHeading | pubmed-meshheading:19306875... | lld:pubmed |
| pubmed-article:19306875 | pubmed:meshHeading | pubmed-meshheading:19306875... | lld:pubmed |
| pubmed-article:19306875 | pubmed:year | 2009 | lld:pubmed |
| pubmed-article:19306875 | pubmed:articleTitle | Beta2-chimaerin binds to EphA receptors and regulates cell migration. | lld:pubmed |
| pubmed-article:19306875 | pubmed:affiliation | Laboratory of Molecular Neurobiology, Graduate School of Biostudies, Kyoto University, Yoshidakonoe-cho, Sakyo-ku, Kyoto 606-8501, Japan. | lld:pubmed |
| pubmed-article:19306875 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:19306875 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| entrez-gene:1124 | entrezgene:pubmed | pubmed-article:19306875 | lld:entrezgene |
| entrez-gene:69993 | entrezgene:pubmed | pubmed-article:19306875 | lld:entrezgene |
| http://linkedlifedata.com/r... | entrezgene:pubmed | pubmed-article:19306875 | lld:entrezgene |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:19306875 | lld:pubmed |
