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pubmed-article:19207479pubmed:abstractTextWe investigated the relationship between resting heart rate (HR) and two measures of beta-1 receptor sensitivity/blockade: (1) the percentage of maximal predicted heart rate reached during exercise (%MPHR), and (2) the HR increase per unit of circulating norepinephrine (NE) or the chronotropic responsiveness index (CRI) in 28 patients with systolic CHF on chronic beta-blocker therapy. Our results show that resting HR is not associated with HR response during exercise nor with beta-1 receptor sensitivity to circulating NE.lld:pubmed
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pubmed-article:19207479pubmed:dateRevised2010-11-18lld:pubmed
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pubmed-article:19207479pubmed:articleTitleResting heart rate does not reflect the degree of beta-blockade in subjects with heart failure on chronic beta-blocker therapy.lld:pubmed
pubmed-article:19207479pubmed:affiliationDepartment of Medicine, Division of Cardiology, Columbia University Medical Center, New York, NY 10032, USA.lld:pubmed
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