| pubmed-article:19201635 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:19201635 | lifeskim:mentions | umls-concept:C0030705 | lld:lifeskim |
| pubmed-article:19201635 | lifeskim:mentions | umls-concept:C0016658 | lld:lifeskim |
| pubmed-article:19201635 | lifeskim:mentions | umls-concept:C0035647 | lld:lifeskim |
| pubmed-article:19201635 | lifeskim:mentions | umls-concept:C0205307 | lld:lifeskim |
| pubmed-article:19201635 | lifeskim:mentions | umls-concept:C1443182 | lld:lifeskim |
| pubmed-article:19201635 | lifeskim:mentions | umls-concept:C1441506 | lld:lifeskim |
| pubmed-article:19201635 | lifeskim:mentions | umls-concept:C1707391 | lld:lifeskim |
| pubmed-article:19201635 | lifeskim:mentions | umls-concept:C0444686 | lld:lifeskim |
| pubmed-article:19201635 | lifeskim:mentions | umls-concept:C1711260 | lld:lifeskim |
| pubmed-article:19201635 | lifeskim:mentions | umls-concept:C1515021 | lld:lifeskim |
| pubmed-article:19201635 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:19201635 | pubmed:dateCreated | 2009-5-11 | lld:pubmed |
| pubmed-article:19201635 | pubmed:abstractText | The World Health Organization fracture risk assessment tool (FRAX) uses clinical risk factors to predict the patient's 10-yr probability of sustaining a hip or other major osteoporosis-related fracture. Inclusion of the femoral neck T-score is optional in the calculation. We evaluated the impact of including the T-score in the calculation of fracture risk and resultant treatment recommendation. We retrospectively reviewed charts of 180 white women scanned on a Hologic dual-energy X-ray absorptiometry (DXA). FRAX scores were calculated with T-scores (FRAX+) and without T-scores (FRAX-). We compared the National Osteoporosis Foundation (NOF) treatment recommendations (>or=20% risk of a major osteoporotic fracture or >or=3% risk of hip fracture for osteopenic patients) between FRAX+ and FRAX- scores. Agreement between FRAX+ and FRAX- was 89.4%. Disagreement occurred in 2 distinct subgroups of patients (10.6% of cases), that is, FRAX+ scores exceeded the NOF recommended treatment thresholds and FRAX- scores did not, or vice versa. One subgroup comprised older patients with normal T-scores for whom FRAX- scores exceeded the treatment threshold. The second subgroup comprised younger patients with high body mass index (BMI) and low T-scores for whom FRAX- scores did not exceed the treatment threshold. FRAX scores generated without T-scores may lead to treatment recommendations for patients who have normal bone mineral density and no treatment recommendations for patients who have osteoporosis. T-scores should be used for optimal application of FRAX. | lld:pubmed |
| pubmed-article:19201635 | pubmed:language | eng | lld:pubmed |
| pubmed-article:19201635 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19201635 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:19201635 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:19201635 | pubmed:issn | 1094-6950 | lld:pubmed |
| pubmed-article:19201635 | pubmed:author | pubmed-author:HamdyRonald... | lld:pubmed |
| pubmed-article:19201635 | pubmed:author | pubmed-author:KiebzakGary... | lld:pubmed |
| pubmed-article:19201635 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:19201635 | pubmed:volume | 12 | lld:pubmed |
| pubmed-article:19201635 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:19201635 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:19201635 | pubmed:pagination | 158-61 | lld:pubmed |
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| pubmed-article:19201635 | pubmed:articleTitle | Variance in 10-year fracture risk calculated with and without T-scores in select subgroups of normal and osteoporotic patients. | lld:pubmed |
| pubmed-article:19201635 | pubmed:affiliation | Osteoporosis Center, East Tennessee State University, Johnson City, TN, USA; VAMC, Johnson City, TN, USA. | lld:pubmed |
| pubmed-article:19201635 | pubmed:publicationType | Journal Article | lld:pubmed |
