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pubmed-article:19159475pubmed:abstractTextOpioid addiction is a chronic, relapsing disease and remains a major public health challenge. Despite important expansions of access to conventional treatments, there are still significant proportions of affected individuals who remain outside the reach of the current treatment system and who contribute disproportionately to health care and criminal justice costs as well as to public disorder associated with drug addiction.The NAOMI study is a Phase III randomized clinical trial comparing injectable heroin maintenance to oral methadone. The study has ethics board approval at its Montréal and Vancouver sites, as well as from the University of Toronto, the New York Academy of Medicine and Johns Hopkins University.The main objective of the NAOMI Study is to determine whether the closely supervised provision of injectable, pharmaceutical-grade opioid agonist is more effective than methadone alone in recruiting, retaining, and benefiting chronic, opioid-dependent, injection drug users who are resistant to current standard treatment options.lld:pubmed
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pubmed-article:19159475pubmed:statusPubMed-not-MEDLINElld:pubmed
pubmed-article:19159475pubmed:issn1477-7517lld:pubmed
pubmed-article:19159475pubmed:authorpubmed-author:SchechterMart...lld:pubmed
pubmed-article:19159475pubmed:authorpubmed-author:LalibertéNanc...lld:pubmed
pubmed-article:19159475pubmed:authorpubmed-author:Oviedo-Joekes...lld:pubmed
pubmed-article:19159475pubmed:authorpubmed-author:GartryCandice...lld:pubmed
pubmed-article:19159475pubmed:issnTypeElectroniclld:pubmed
pubmed-article:19159475pubmed:volume6lld:pubmed
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pubmed-article:19159475pubmed:dateRevised2011-10-20lld:pubmed
pubmed-article:19159475pubmed:year2009lld:pubmed
pubmed-article:19159475pubmed:articleTitleNAOMI: The trials and tribulations of implementing a heroin assisted treatment study in North America.lld:pubmed
pubmed-article:19159475pubmed:affiliationCIHR Canadian HIV Trials Network and the Centre for Health Evaluation & Outcome Sciences (CHEOS), Vancouver, BC, Canada. cgartry@shaw.calld:pubmed
pubmed-article:19159475pubmed:publicationTypeJournal Articlelld:pubmed