| pubmed-article:19121913 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:19121913 | lifeskim:mentions | umls-concept:C0038627 | lld:lifeskim |
| pubmed-article:19121913 | lifeskim:mentions | umls-concept:C0680730 | lld:lifeskim |
| pubmed-article:19121913 | lifeskim:mentions | umls-concept:C1511790 | lld:lifeskim |
| pubmed-article:19121913 | lifeskim:mentions | umls-concept:C0201699 | lld:lifeskim |
| pubmed-article:19121913 | lifeskim:mentions | umls-concept:C1705957 | lld:lifeskim |
| pubmed-article:19121913 | lifeskim:mentions | umls-concept:C1148554 | lld:lifeskim |
| pubmed-article:19121913 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:19121913 | pubmed:dateCreated | 2009-2-9 | lld:pubmed |
| pubmed-article:19121913 | pubmed:abstractText | A simple method based on capillary electrophoresis with a capacitively coupled contactless conductivity detector (CE-C(4)D) was developed for the determination of suxamethonium (SUX) in a pharmaceutical formulation. A hydro-organic mixture, consisting of 100mM Tris-acetate buffer at pH 4.2 and acetonitrile (90:10, v/v), was selected as background electrolyte (BGE). The applied voltage was 30kV, and the sample injection was performed in the hydrodynamic mode. All analyses were carried out in a fused silica capillary with an internal diameter of 50 microm and a total length of 64.5cm. Under these conditions, a complete separation between SUX, sodium ions and the main degradation products (choline) was achieved in less than 4min. The presence of acetonitrile in the BGE allowed a reduction of SUX adsorption on the capillary wall. The CE-C(4)D method was validated, and trueness values between 98.8% and 101.1% were obtained with repeatability and intermediate precision values of 0.7-1.3% and 1.2-1.6%, respectively. Therefore, this method was found appropriate for controlling pharmaceutical formulations containing suxamethonium and degradation products. | lld:pubmed |
| pubmed-article:19121913 | pubmed:language | eng | lld:pubmed |
| pubmed-article:19121913 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19121913 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:19121913 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19121913 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19121913 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19121913 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19121913 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19121913 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19121913 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19121913 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19121913 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19121913 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19121913 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:19121913 | pubmed:month | Feb | lld:pubmed |
| pubmed-article:19121913 | pubmed:issn | 0731-7085 | lld:pubmed |
| pubmed-article:19121913 | pubmed:author | pubmed-author:VeutheyJean-L... | lld:pubmed |
| pubmed-article:19121913 | pubmed:author | pubmed-author:RudazSergeS | lld:pubmed |
| pubmed-article:19121913 | pubmed:author | pubmed-author:BonnabryPasca... | lld:pubmed |
| pubmed-article:19121913 | pubmed:author | pubmed-author:Fleury-Souver... | lld:pubmed |
| pubmed-article:19121913 | pubmed:author | pubmed-author:NussbaumerSus... | lld:pubmed |
| pubmed-article:19121913 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:19121913 | pubmed:day | 20 | lld:pubmed |
| pubmed-article:19121913 | pubmed:volume | 49 | lld:pubmed |
| pubmed-article:19121913 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:19121913 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:19121913 | pubmed:pagination | 333-7 | lld:pubmed |
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| pubmed-article:19121913 | pubmed:year | 2009 | lld:pubmed |
| pubmed-article:19121913 | pubmed:articleTitle | Determination of suxamethonium in a pharmaceutical formulation by capillary electrophoresis with contactless conductivity detection (CE-C(4)D). | lld:pubmed |
| pubmed-article:19121913 | pubmed:affiliation | Pharmacy, University Hospitals of Geneva , Geneva, Switzerland. | lld:pubmed |
| pubmed-article:19121913 | pubmed:publicationType | Journal Article | lld:pubmed |
