Statements in which the resource exists.
SubjectPredicateObjectContext
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pubmed-article:19117276pubmed:issue9lld:pubmed
pubmed-article:19117276pubmed:dateCreated2009-8-27lld:pubmed
pubmed-article:19117276pubmed:abstractTextThe functional components of the human motor system that are used to retrieve and execute simple intransitive hand gestures were identified with a repetition suppression (RS) paradigm. Participants performed movements with the right hand to text instructions in a rapid event related design with a pseudo-random stimulus order. Brain areas associated with action retrieval were identified by comparing trials where an action was repeated to trials that involved a new action. Performance of a novel action, collapsed across individual actions, resulted in significantly greater activity in a left hemisphere predominant fronto-parietal circuit involving inferior frontal gyrus and inferior parietal cortex (supramarginal gyrus). This is consistent with previous action retrieval tasks using go, no-go paradigms and lesion studies of patients with apraxia that emphasize a role of these areas in action organization. In addition, RS effects were present in left primary sensorimotor cortex. These effects cannot be ascribed to kinematic differences, simple action related activity or differences of cognitive set. Significant RS effects for action retrieval could be identified with as little as 5 min of fMRI data and underscores the potential of using RS to characterize representational structure within the motor system.lld:pubmed
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pubmed-article:19117276pubmed:issn1097-0193lld:pubmed
pubmed-article:19117276pubmed:authorpubmed-author:GraftonScott...lld:pubmed
pubmed-article:19117276pubmed:authorpubmed-author:HamiltonAnton...lld:pubmed
pubmed-article:19117276pubmed:copyrightInfo2008 Wiley-Liss, Inc.lld:pubmed
pubmed-article:19117276pubmed:issnTypeElectroniclld:pubmed
pubmed-article:19117276pubmed:volume30lld:pubmed
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pubmed-article:19117276pubmed:year2009lld:pubmed
pubmed-article:19117276pubmed:articleTitleRepetition suppression for performed hand gestures revealed by fMRI.lld:pubmed
pubmed-article:19117276pubmed:affiliationSchool of Psychology, University of Nottingham, Nottingham, United Kingdom. antonia.hamilton@nottingham.ac.uklld:pubmed
pubmed-article:19117276pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:19117276pubmed:publicationTypeResearch Support, U.S. Gov't, Non-P.H.S.lld:pubmed
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pubmed-article:19117276pubmed:publicationTypeResearch Support, N.I.H., Extramurallld:pubmed