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pubmed-article:19086019pubmed:abstractTextThe bladder exstrophy-epispadias complex represents a spectrum of urogenital anomalies in which part or all of the distal urinary tract fail to close and are exposed on the outer abdominal wall. Previous studies are suggestive of an underlying multifactorial mode of inheritance. However, no genetic or nongenetic factor has been identified so far. In this study, we sought risk loci by parametric and nonparametric linkage analysis, searching for homozygous segments, and more complex inherited loci, respectively.lld:pubmed
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pubmed-article:19086019pubmed:authorpubmed-author:LudwigMichael...lld:pubmed
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pubmed-article:19086019pubmed:copyrightInfo(c) 2008 Wiley-Liss, Inc.lld:pubmed
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pubmed-article:19086019pubmed:year2009lld:pubmed
pubmed-article:19086019pubmed:articleTitleGenome-wide linkage scan for bladder exstrophy-epispadias complex.lld:pubmed
pubmed-article:19086019pubmed:affiliationDepartment of Clinical Biochemistry and Pharmacology, University of Bonn, Sigmund-Freud-Strasse 25, Bonn. mludwig@uni-bonn.delld:pubmed
pubmed-article:19086019pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:19086019pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed