| pubmed-article:19035793 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:19035793 | lifeskim:mentions | umls-concept:C0011923 | lld:lifeskim |
| pubmed-article:19035793 | lifeskim:mentions | umls-concept:C0037098 | lld:lifeskim |
| pubmed-article:19035793 | lifeskim:mentions | umls-concept:C0009924 | lld:lifeskim |
| pubmed-article:19035793 | lifeskim:mentions | umls-concept:C0444669 | lld:lifeskim |
| pubmed-article:19035793 | lifeskim:mentions | umls-concept:C1450054 | lld:lifeskim |
| pubmed-article:19035793 | lifeskim:mentions | umls-concept:C1513743 | lld:lifeskim |
| pubmed-article:19035793 | lifeskim:mentions | umls-concept:C0303920 | lld:lifeskim |
| pubmed-article:19035793 | lifeskim:mentions | umls-concept:C1258084 | lld:lifeskim |
| pubmed-article:19035793 | lifeskim:mentions | umls-concept:C1710360 | lld:lifeskim |
| pubmed-article:19035793 | pubmed:issue | 12 | lld:pubmed |
| pubmed-article:19035793 | pubmed:dateCreated | 2008-12-18 | lld:pubmed |
| pubmed-article:19035793 | pubmed:abstractText | Silica particles as a nanoparticulate carrier material for contrast agents have received considerable attention the past few years, since the material holds great promise for biomedical applications. A key feature for successful application of this material in vivo is biocompatibility, which may be significantly improved by appropriate surface modification. In this study, we report a novel strategy to coat silica particles with a dense monolayer of paramagnetic and PEGylated lipids. The silica nanoparticles carry a quantum dot in their center and are made target-specific by the conjugation of multiple alphavbeta3-integrin-specific RGD-peptides. We demonstrate their specific uptake by endothelial cells in vitro using fluorescence microscopy, quantitative fluorescence imaging, and magnetic resonance imaging. The lipid-coated silica particles introduced here represent a new platform for nanoparticulate multimodality contrast agents. | lld:pubmed |
| pubmed-article:19035793 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19035793 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19035793 | pubmed:language | eng | lld:pubmed |
| pubmed-article:19035793 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19035793 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:19035793 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19035793 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19035793 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19035793 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19035793 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19035793 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19035793 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:19035793 | pubmed:month | Dec | lld:pubmed |
| pubmed-article:19035793 | pubmed:issn | 1520-4812 | lld:pubmed |
| pubmed-article:19035793 | pubmed:author | pubmed-author:NicolayKlaasK | lld:pubmed |
| pubmed-article:19035793 | pubmed:author | pubmed-author:FayadZahi AZA | lld:pubmed |
| pubmed-article:19035793 | pubmed:author | pubmed-author:GriffioenArja... | lld:pubmed |
| pubmed-article:19035793 | pubmed:author | pubmed-author:StrijkersGust... | lld:pubmed |
| pubmed-article:19035793 | pubmed:author | pubmed-author:Vanmaekelberg... | lld:pubmed |
| pubmed-article:19035793 | pubmed:author | pubmed-author:CormodeDavid... | lld:pubmed |
| pubmed-article:19035793 | pubmed:author | pubmed-author:de Mello... | lld:pubmed |
| pubmed-article:19035793 | pubmed:author | pubmed-author:MeijerinkAndr... | lld:pubmed |
| pubmed-article:19035793 | pubmed:author | pubmed-author:MulderWillem... | lld:pubmed |
| pubmed-article:19035793 | pubmed:author | pubmed-author:CastermansKar... | lld:pubmed |
| pubmed-article:19035793 | pubmed:author | pubmed-author:KooleRolfR | lld:pubmed |
| pubmed-article:19035793 | pubmed:author | pubmed-author:van... | lld:pubmed |
| pubmed-article:19035793 | pubmed:author | pubmed-author:HilhorstJanJ | lld:pubmed |
| pubmed-article:19035793 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:19035793 | pubmed:volume | 19 | lld:pubmed |
| pubmed-article:19035793 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:19035793 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:19035793 | pubmed:pagination | 2471-9 | lld:pubmed |
| pubmed-article:19035793 | pubmed:dateRevised | 2010-11-18 | lld:pubmed |
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| pubmed-article:19035793 | pubmed:meshHeading | pubmed-meshheading:19035793... | lld:pubmed |
| pubmed-article:19035793 | pubmed:meshHeading | pubmed-meshheading:19035793... | lld:pubmed |
| pubmed-article:19035793 | pubmed:meshHeading | pubmed-meshheading:19035793... | lld:pubmed |
| pubmed-article:19035793 | pubmed:meshHeading | pubmed-meshheading:19035793... | lld:pubmed |
| pubmed-article:19035793 | pubmed:meshHeading | pubmed-meshheading:19035793... | lld:pubmed |
| pubmed-article:19035793 | pubmed:meshHeading | pubmed-meshheading:19035793... | lld:pubmed |
| pubmed-article:19035793 | pubmed:meshHeading | pubmed-meshheading:19035793... | lld:pubmed |
| pubmed-article:19035793 | pubmed:year | 2008 | lld:pubmed |
| pubmed-article:19035793 | pubmed:articleTitle | Paramagnetic lipid-coated silica nanoparticles with a fluorescent quantum dot core: a new contrast agent platform for multimodality imaging. | lld:pubmed |
| pubmed-article:19035793 | pubmed:affiliation | Condensed Matter and Interfaces, University Utrecht, P.O. Box 80000, 3508 TA Utrecht, The Netherlands. | lld:pubmed |
| pubmed-article:19035793 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:19035793 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| pubmed-article:19035793 | pubmed:publicationType | Research Support, N.I.H., Extramural | lld:pubmed |
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