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pubmed-article:19032826pubmed:abstractText17Beta-estradiol, estrone, and several of their hydroxylated metabolites, have been found to be significantly increased in synovial fluid of rheumatoid arthritis (RA) patients. In this study, we investigated whether the estrogen metabolites are able to exert direct effects on monocyte cell proliferation, which is important in RA synovial tissue activation and growth.lld:pubmed
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pubmed-article:19032826pubmed:articleTitleHydroxylated estrogen metabolites influence the proliferation of cultured human monocytes: possible role in synovial tissue hyperplasia.lld:pubmed
pubmed-article:19032826pubmed:affiliationResearch Laboratory, Academic Clinical Unit of Rheumatology, Postgraduate School of Rheumatology, University of Genova, Genova, Italy.lld:pubmed
pubmed-article:19032826pubmed:publicationTypeJournal Articlelld:pubmed
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