| pubmed-article:18955447 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:18955447 | lifeskim:mentions | umls-concept:C0030705 | lld:lifeskim |
| pubmed-article:18955447 | lifeskim:mentions | umls-concept:C0001675 | lld:lifeskim |
| pubmed-article:18955447 | lifeskim:mentions | umls-concept:C0280100 | lld:lifeskim |
| pubmed-article:18955447 | lifeskim:mentions | umls-concept:C1579259 | lld:lifeskim |
| pubmed-article:18955447 | lifeskim:mentions | umls-concept:C1704259 | lld:lifeskim |
| pubmed-article:18955447 | lifeskim:mentions | umls-concept:C1705987 | lld:lifeskim |
| pubmed-article:18955447 | lifeskim:mentions | umls-concept:C2347619 | lld:lifeskim |
| pubmed-article:18955447 | lifeskim:mentions | umls-concept:C0920321 | lld:lifeskim |
| pubmed-article:18955447 | lifeskim:mentions | umls-concept:C1709060 | lld:lifeskim |
| pubmed-article:18955447 | lifeskim:mentions | umls-concept:C0679622 | lld:lifeskim |
| pubmed-article:18955447 | lifeskim:mentions | umls-concept:C0205314 | lld:lifeskim |
| pubmed-article:18955447 | pubmed:issue | 34 | lld:pubmed |
| pubmed-article:18955447 | pubmed:dateCreated | 2008-11-27 | lld:pubmed |
| pubmed-article:18955447 | pubmed:abstractText | We conducted a first-in-man (to our knowledge) phase I study to determine the dose-limiting toxicities (DLTs), characterize the pharmacokinetic profile, and document any antitumor activity of ON 01910.Na, a new chemical entity that arrests cancer cells in G(2)/M by modulating mitotic regulatory pathways including polo-like kinase 1 (Plk1). | lld:pubmed |
| pubmed-article:18955447 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18955447 | pubmed:language | eng | lld:pubmed |
| pubmed-article:18955447 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18955447 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:18955447 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18955447 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18955447 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18955447 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18955447 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18955447 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18955447 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18955447 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18955447 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:18955447 | pubmed:month | Dec | lld:pubmed |
| pubmed-article:18955447 | pubmed:issn | 1527-7755 | lld:pubmed |
| pubmed-article:18955447 | pubmed:author | pubmed-author:DonehowerRoss... | lld:pubmed |
| pubmed-article:18955447 | pubmed:author | pubmed-author:LiJingJ | lld:pubmed |
| pubmed-article:18955447 | pubmed:author | pubmed-author:BakerSharyn... | lld:pubmed |
| pubmed-article:18955447 | pubmed:author | pubmed-author:HidalgoManuel... | lld:pubmed |
| pubmed-article:18955447 | pubmed:author | pubmed-author:RudekMichelle... | lld:pubmed |
| pubmed-article:18955447 | pubmed:author | pubmed-author:LaheruDanielD | lld:pubmed |
| pubmed-article:18955447 | pubmed:author | pubmed-author:JimenoAntonio... | lld:pubmed |
| pubmed-article:18955447 | pubmed:author | pubmed-author:MessersmithWe... | lld:pubmed |
| pubmed-article:18955447 | pubmed:author | pubmed-author:ManiarManojM | lld:pubmed |
| pubmed-article:18955447 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:18955447 | pubmed:day | 1 | lld:pubmed |
| pubmed-article:18955447 | pubmed:volume | 26 | lld:pubmed |
| pubmed-article:18955447 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:18955447 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:18955447 | pubmed:pagination | 5504-10 | lld:pubmed |
| pubmed-article:18955447 | pubmed:dateRevised | 2011-11-2 | lld:pubmed |
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| pubmed-article:18955447 | pubmed:meshHeading | pubmed-meshheading:18955447... | lld:pubmed |
| pubmed-article:18955447 | pubmed:meshHeading | pubmed-meshheading:18955447... | lld:pubmed |
| pubmed-article:18955447 | pubmed:meshHeading | pubmed-meshheading:18955447... | lld:pubmed |
| pubmed-article:18955447 | pubmed:meshHeading | pubmed-meshheading:18955447... | lld:pubmed |
| pubmed-article:18955447 | pubmed:meshHeading | pubmed-meshheading:18955447... | lld:pubmed |
| pubmed-article:18955447 | pubmed:meshHeading | pubmed-meshheading:18955447... | lld:pubmed |
| pubmed-article:18955447 | pubmed:meshHeading | pubmed-meshheading:18955447... | lld:pubmed |
| pubmed-article:18955447 | pubmed:year | 2008 | lld:pubmed |
| pubmed-article:18955447 | pubmed:articleTitle | Phase I study of ON 01910.Na, a novel modulator of the Polo-like kinase 1 pathway, in adult patients with solid tumors. | lld:pubmed |
| pubmed-article:18955447 | pubmed:affiliation | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University, Baltimore, MD, USA. antonio.jimeno@uchsc.edu | lld:pubmed |
| pubmed-article:18955447 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:18955447 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| pubmed-article:18955447 | pubmed:publicationType | Clinical Trial, Phase I | lld:pubmed |
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| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:18955447 | lld:pubmed |
