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pubmed-article:18837969pubmed:abstractTextGene expression levels in a given cell can be influenced by different factors, namely pharmacological or medical treatments. The response to a given stimulus is usually different for different genes and may depend on time. One of the goals of modern molecular biology is the high-throughput identification of genes associated with a particular treatment or a biological process of interest. From methodological and computational point of view, analyzing high-dimensional time course microarray data requires very specific set of tools which are usually not included in standard software packages. Recently, the authors of this paper developed a fully Bayesian approach which allows one to identify differentially expressed genes in a 'one-sample' time-course microarray experiment, to rank them and to estimate their expression profiles. The method is based on explicit expressions for calculations and, hence, very computationally efficient.lld:pubmed
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pubmed-article:18837969pubmed:authorpubmed-author:CutilloLuisaLlld:pubmed
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pubmed-article:18837969pubmed:dateRevised2009-11-18lld:pubmed
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pubmed-article:18837969pubmed:articleTitleBATS: a Bayesian user-friendly software for analyzing time series microarray experiments.lld:pubmed
pubmed-article:18837969pubmed:affiliationIstituto per le Applicazioni del Calcolo, Mauro Picone, CNR-Napoli, Italy. c.angelini@iac.cnr.itlld:pubmed
pubmed-article:18837969pubmed:publicationTypeJournal Articlelld:pubmed
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