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pubmed-article:18808670pubmed:abstractTextThe central nervous tissue contains diverse subtypes of neurons with characteristic morphological and physiological features and different neurotransmitter phenotypes. The generation of neurons with defined neurotransmitter phenotypes seems to be governed by factors differently expressed along the anterior-posterior and dorsal-ventral body axes. The mechanisms of the cell-type determination, however, are poorly understood. Selected neuronal phenotypes had been generated from embryonic stem (ES) cells, but similar results were not obtained on more restricted neural stem cells, presumably due to the lack of homogeneous neural stem cell populations as a starting material.lld:pubmed
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pubmed-article:18808670pubmed:authorpubmed-author:MadarászEmíli...lld:pubmed
pubmed-article:18808670pubmed:authorpubmed-author:HerberthBaláz...lld:pubmed
pubmed-article:18808670pubmed:authorpubmed-author:GóczaElenElld:pubmed
pubmed-article:18808670pubmed:authorpubmed-author:DemeterKornél...lld:pubmed
pubmed-article:18808670pubmed:authorpubmed-author:VargaBalázs...lld:pubmed
pubmed-article:18808670pubmed:authorpubmed-author:HádingerNóraNlld:pubmed
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pubmed-article:18808670pubmed:articleTitleGeneration of diverse neuronal subtypes in cloned populations of stem-like cells.lld:pubmed
pubmed-article:18808670pubmed:affiliationLaboratory of Cellular and Developmental Neurobiology, Institute of Experimental Medicine of Hungarian Academy of Sciences, Budapest, Hungary. vargab@koki.hulld:pubmed
pubmed-article:18808670pubmed:publicationTypeJournal Articlelld:pubmed
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