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pubmed-article:18725440pubmed:abstractTextFluoroquinolone resistance in Streptococcus pneumoniae mainly involves stepwise mutations predominantly in the parC and gyrA genes. We have developed a single-run real-time PCR assay for detection of the four most common mutations in the quinolone resistance-determining regions of these genes. This assay provides a useful tool for both clinical and epidemiological use.lld:pubmed
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pubmed-article:18725440pubmed:articleTitleReal-time PCR detection of gyrA and parC mutations in Streptococcus pneumoniae.lld:pubmed
pubmed-article:18725440pubmed:affiliationInstitut Pasteur de Nouvelle-Calédonie, Laboratoire d'Epidémiologie Moléculaire, Nouméa, New Caledonia.lld:pubmed
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