18708154

Source:http://linkedlifedata.com/resource/pubmed/id/18708154

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Subject	Predicate	Object	Context
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pubmed-article:18708154	lifeskim:mentions	umls-concept:C1704259	lld:lifeskim
pubmed-article:18708154	lifeskim:mentions	umls-concept:C1150611	lld:lifeskim
pubmed-article:18708154	lifeskim:mentions	umls-concept:C1705987	lld:lifeskim
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pubmed-article:18708154	lifeskim:mentions	umls-concept:C1548425	lld:lifeskim
pubmed-article:18708154	pubmed:issue	4	lld:pubmed
pubmed-article:18708154	pubmed:dateCreated	2008-12-8	lld:pubmed
pubmed-article:18708154	pubmed:abstractText	The suppressor of cytokine signalling (SOCS) proteins were, as their name suggests, first described as inhibitors of cytokine signalling. While their actions clearly now extend to other intracellular pathways, they remain key negative regulators of cytokine and growth factor signalling. In this review we focus on the mechanics of SOCS action and the complexities of the mouse models that have underpinned our current understanding of SOCS biology.	lld:pubmed
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