| pubmed-article:18705840 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:18705840 | lifeskim:mentions | umls-concept:C0156543 | lld:lifeskim |
| pubmed-article:18705840 | lifeskim:mentions | umls-concept:C1704410 | lld:lifeskim |
| pubmed-article:18705840 | lifeskim:mentions | umls-concept:C1519315 | lld:lifeskim |
| pubmed-article:18705840 | lifeskim:mentions | umls-concept:C0017262 | lld:lifeskim |
| pubmed-article:18705840 | lifeskim:mentions | umls-concept:C1540289 | lld:lifeskim |
| pubmed-article:18705840 | lifeskim:mentions | umls-concept:C1546857 | lld:lifeskim |
| pubmed-article:18705840 | lifeskim:mentions | umls-concept:C2911684 | lld:lifeskim |
| pubmed-article:18705840 | lifeskim:mentions | umls-concept:C0591833 | lld:lifeskim |
| pubmed-article:18705840 | lifeskim:mentions | umls-concept:C0185117 | lld:lifeskim |
| pubmed-article:18705840 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:18705840 | pubmed:dateCreated | 2008-8-18 | lld:pubmed |
| pubmed-article:18705840 | pubmed:abstractText | Lipopolysaccharide (LPS) acts via tlr4 to promote Th1 cytokine secretion and abortions. LPS is an essential co-factor in spontaneous abortion in the CBA x DBA/2 model and in stress-triggered abortions. In the CBA x DBA/2 model, C3a, C5a, and fgl2 prothrombinase participate in triggering inflammation that terminates embryo viability. As fgl2 prothrombinase (via thrombin) can generate C5a, it was predicted that LPS-driven abortions (which require fgl2) would be independent of C3. CD200Fc can prevent abortions in the CBA x DBA/2 model, but an action through Fc could not be excluded. | lld:pubmed |
| pubmed-article:18705840 | pubmed:language | eng | lld:pubmed |
| pubmed-article:18705840 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18705840 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:18705840 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18705840 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18705840 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18705840 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18705840 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18705840 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18705840 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18705840 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18705840 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:18705840 | pubmed:month | Aug | lld:pubmed |
| pubmed-article:18705840 | pubmed:issn | 1046-7408 | lld:pubmed |
| pubmed-article:18705840 | pubmed:author | pubmed-author:MolinaHectorH | lld:pubmed |
| pubmed-article:18705840 | pubmed:author | pubmed-author:LevyGary AGA | lld:pubmed |
| pubmed-article:18705840 | pubmed:author | pubmed-author:YangSunS | lld:pubmed |
| pubmed-article:18705840 | pubmed:author | pubmed-author:ClarkDavid... | lld:pubmed |
| pubmed-article:18705840 | pubmed:author | pubmed-author:GorczynskiReg... | lld:pubmed |
| pubmed-article:18705840 | pubmed:author | pubmed-author:YuGaryG | lld:pubmed |
| pubmed-article:18705840 | pubmed:author | pubmed-author:FoersterKatha... | lld:pubmed |
| pubmed-article:18705840 | pubmed:author | pubmed-author:ManuelJustinJ | lld:pubmed |
| pubmed-article:18705840 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:18705840 | pubmed:volume | 60 | lld:pubmed |
| pubmed-article:18705840 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:18705840 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:18705840 | pubmed:pagination | 135-40 | lld:pubmed |
| pubmed-article:18705840 | pubmed:meshHeading | pubmed-meshheading:18705840... | lld:pubmed |
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| pubmed-article:18705840 | pubmed:meshHeading | pubmed-meshheading:18705840... | lld:pubmed |
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| pubmed-article:18705840 | pubmed:meshHeading | pubmed-meshheading:18705840... | lld:pubmed |
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| pubmed-article:18705840 | pubmed:meshHeading | pubmed-meshheading:18705840... | lld:pubmed |
| pubmed-article:18705840 | pubmed:meshHeading | pubmed-meshheading:18705840... | lld:pubmed |
| pubmed-article:18705840 | pubmed:year | 2008 | lld:pubmed |
| pubmed-article:18705840 | pubmed:articleTitle | LPS-induced murine abortions require C5 but not C3, and are prevented by upregulating expression of the CD200 tolerance signaling molecule. | lld:pubmed |
| pubmed-article:18705840 | pubmed:affiliation | Toronto General Research Institute & CIHR Group on Cellular and Molecular Mechanisms of Organ Injury, Institute of Medical Sciences, University of Toronto, Toronto, Ontario, Canada. | lld:pubmed |
| pubmed-article:18705840 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:18705840 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| entrez-gene:17470 | entrezgene:pubmed | pubmed-article:18705840 | lld:entrezgene |
| http://linkedlifedata.com/r... | entrezgene:pubmed | pubmed-article:18705840 | lld:entrezgene |
