Published work links adult lymphoid tissue-inducer cells (LTi) with T cell-dependent antibody responses. In this issue of Immunity, Tsuji et al. (2008) associate LTi with T cell-independent IgA antibody responses in the gut.
Medical Research Council Centre for Immune Regulation, Institute for Biomedical Research, Birmingham Medical School, Vincent Drive, Birmingham B15 2TT, UK. p.j.l.lane@bham.ac.uk.
