| pubmed-article:18671827 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:18671827 | lifeskim:mentions | umls-concept:C1257890 | lld:lifeskim |
| pubmed-article:18671827 | lifeskim:mentions | umls-concept:C0442592 | lld:lifeskim |
| pubmed-article:18671827 | lifeskim:mentions | umls-concept:C0425245 | lld:lifeskim |
| pubmed-article:18671827 | lifeskim:mentions | umls-concept:C1261552 | lld:lifeskim |
| pubmed-article:18671827 | pubmed:issue | 4 | lld:pubmed |
| pubmed-article:18671827 | pubmed:dateCreated | 2008-10-30 | lld:pubmed |
| pubmed-article:18671827 | pubmed:abstractText | High mobility group box (HMGB)1, originally described as a nuclear protein that binds to and modifies DNA, is now regarded as a central mediator of inflammation by acting as a cytokine. HMGB1 is postulated to be particularly important as a late acting mediator of lethal septicaemia in mice. Furthermore, it has been suggested that HMGB1 plays a role in clinical conditions such as autoimmunity, acute ischaemia-reperfusion injury, cardiovascular disease and cancer. HMGB1 has emerged as a candidate for therapeutic intervention in various disease conditions. However, further basic and clinical studies are warranted to confirm the roles played by HMGB1 in clinical medicine. | lld:pubmed |
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| pubmed-article:18671827 | pubmed:language | eng | lld:pubmed |
| pubmed-article:18671827 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18671827 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:18671827 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18671827 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18671827 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:18671827 | pubmed:issn | 1466-609X | lld:pubmed |
| pubmed-article:18671827 | pubmed:author | pubmed-author:MollnesTom... | lld:pubmed |
| pubmed-article:18671827 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:18671827 | pubmed:volume | 12 | lld:pubmed |
| pubmed-article:18671827 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:18671827 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:18671827 | pubmed:pagination | 168 | lld:pubmed |
| pubmed-article:18671827 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
| pubmed-article:18671827 | pubmed:meshHeading | pubmed-meshheading:18671827... | lld:pubmed |
| pubmed-article:18671827 | pubmed:meshHeading | pubmed-meshheading:18671827... | lld:pubmed |
| pubmed-article:18671827 | pubmed:meshHeading | pubmed-meshheading:18671827... | lld:pubmed |
| pubmed-article:18671827 | pubmed:meshHeading | pubmed-meshheading:18671827... | lld:pubmed |
| pubmed-article:18671827 | pubmed:meshHeading | pubmed-meshheading:18671827... | lld:pubmed |
| pubmed-article:18671827 | pubmed:meshHeading | pubmed-meshheading:18671827... | lld:pubmed |
| pubmed-article:18671827 | pubmed:year | 2008 | lld:pubmed |
| pubmed-article:18671827 | pubmed:articleTitle | High mobility group box-1 protein--one step closer to the clinic? | lld:pubmed |
| pubmed-article:18671827 | pubmed:publicationType | Editorial | lld:pubmed |
| pubmed-article:18671827 | pubmed:publicationType | Comment | lld:pubmed |
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