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pubmed-article:18665349pubmed:abstractTextGrowth of alkaliphilic Bacillus halodurans C-125 both on agar plates and in liquid culture was inhibited by methyl-beta-cyclodextrin (CD). Furthermore, resting cells of the strain were lysed by contact with methyl-beta-CD higher than 10 mM. alpha-CD also showed lysis activity against Bacillus and related strains. The activity was not observed with Gram-negative and Gram-positive bacteria except for Bacillus strains. Fluorescence staining and scanning electron microscopy of cells revealed that methyl-beta-CD disrupted cell membranes, and consequently, the cells were lysed. This is a novel physiological property of CDs.lld:pubmed
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pubmed-article:18665349pubmed:articleTitleAntibacterial activity of cyclodextrins against Bacillus strains.lld:pubmed
pubmed-article:18665349pubmed:affiliationExtremobiosphere Research Center of Japan Agency for Marine-Earth Science and Technology (JAMSTEC) 2-15, Natsushima, Yokosuka 237-0061, Japan.lld:pubmed
pubmed-article:18665349pubmed:publicationTypeJournal Articlelld:pubmed